transaminase
- noun
- /trænˈsæməˌneɪs/
- Specialized
- A high level of transaminase in the blood can signal liver inflammation or injury, which may require further investigation.
- alanine transaminase
- aspartate transaminase
- transaminase levels
Examples
-
His plasma bilirubin was slightly raised (34 mmol/L); transaminases were normal, and there was no evidence of hepatic encephalopathy.
Academic text (1999) -
No clinically relevant between-group differences were apparent for changes in vital signs or laboratory safety data, including transaminase levels.
Academic text (2003) -
As statins work through the liver, stop or do not start the statin if transaminase levels are above three times the local laboratory maximum.
Academic text (2015) -
Biochemical abnormalities, particularly elevated liver transaminases, are not uncommon.
Academic text (2007) -
The highest fall in Aspartate transaminase (AST) values was seen in group E (31.62, 34.22, and 35.92) at 20, 40, and 60 minutes.
Academic text (2014) -
Liver function tests: transaminase level (alanine aminotransferase or aspartate aminotransferase) to be done before starting a statin and then at 3 months and 12 months.
Academic text (2015) -
Nevertheless, in most patients receiving IL-12 at the dose regimen used, a flu-like syndrome and transient increases in serum hepatic transaminases occurred.
Academic text (2000) -
The fatal case was in a 71-year-old Lebanese woman hospitalized in a private clinic in Dakar on October 30 with a 4-day history of fever; she had severe thrombocytopenia and elevated transaminase levels.
Academic text (2014) -
Pre-treatment variables independently predictive of sustained loss of HBeAg and HBV DNA include high transaminase levels, low HBV DNA levels, and a history of acute hepatitis.
Academic text (1994) -
Routine blood tests revealed that the patient's transaminase levels were significantly elevated, indicating possible liver damage.
Synonyms
A protein that moves part of an amino acid to another chemical
A protein that moves a small chemical part from one molecule to another
A protein that moves a small chemical part from one amino acid to another helping the body use amino acids
An enzyme in the blood that rises when the liver is damaged
A protein measured in blood that shows liver damage when high
Compounds
- Specialized
A protein measured in blood that shows liver damage when high
- Specialized
An enzyme in the blood that rises when the liver is damaged
Surface Forms
Morphology
transaminase = transaminate (transparent) = trans + amin + ase
Formed by adding the enzyme-forming suffix '-ase' to the verb 'transaminate', following a regular biochemical word-formation pattern.
Etymology
Transaminase breaks into trans- meaning 'across', amine meaning 'an amino group', and the enzyme ending -ase, the same ending as in lactase. So a transaminase is an enzyme that moves an amino group 'across' from one molecule to another, which is why it helps change amino acids.