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transaminase

transaminase

1 9.8
An enzyme that moves an amino group from one amino acid to another in the body
  • noun
  • /trænˈsæməˌneɪs/
  • Specialized
translation icon : transaminasa
  • A high level of transaminase in the blood can signal liver inflammation or injury, which may require further investigation.
  • alanine transaminase
  • aspartate transaminase
  • transaminase levels

Examples

  • His plasma bilirubin was slightly raised (34 mmol/L); transaminases were normal, and there was no evidence of hepatic encephalopathy.

    Academic text (1999)
  • No clinically relevant between-group differences were apparent for changes in vital signs or laboratory safety data, including transaminase levels.

    Academic text (2003)
  • As statins work through the liver, stop or do not start the statin if transaminase levels are above three times the local laboratory maximum.

    Academic text (2015)
  • Biochemical abnormalities, particularly elevated liver transaminases, are not uncommon.

    Academic text (2007)
  • The highest fall in Aspartate transaminase (AST) values was seen in group E (31.62, 34.22, and 35.92) at 20, 40, and 60 minutes.

    Academic text (2014)
  • Liver function tests: transaminase level (alanine aminotransferase or aspartate aminotransferase) to be done before starting a statin and then at 3 months and 12 months.

    Academic text (2015)
  • Nevertheless, in most patients receiving IL-12 at the dose regimen used, a flu-like syndrome and transient increases in serum hepatic transaminases occurred.

    Academic text (2000)
  • The fatal case was in a 71-year-old Lebanese woman hospitalized in a private clinic in Dakar on October 30 with a 4-day history of fever; she had severe thrombocytopenia and elevated transaminase levels.

    Academic text (2014)
  • Pre-treatment variables independently predictive of sustained loss of HBeAg and HBV DNA include high transaminase levels, low HBV DNA levels, and a history of acute hepatitis.

    Academic text (1994)
  • Routine blood tests revealed that the patient's transaminase levels were significantly elevated, indicating possible liver damage.

Synonyms

aminotransferase
vstransaminase
  • Specialized
1 8.8

A protein that moves part of an amino acid to another chemical

is broader, transferring amino groups from amino acids to various compounds
transferase
vstransaminase
  • Specialized
1 8.4

A protein that moves a small chemical part from one molecule to another

is specific to amino group transfer in amino acid metabolism rather than any group
aminopherase
vstransaminase
  • Specialized
9.9

A protein that moves a small chemical part from one amino acid to another helping the body use amino acids

is the general enzyme class performing amino group transfer in metabolism
glutamic oxaloacetic transaminase
vstransaminase
  • Specialized
9.9

An enzyme in the blood that rises when the liver is damaged

is the general amino group transfer enzyme not limited to that substrate pair
glutamic oxalacetic transaminase
vstransaminase
  • Specialized
8.1

A protein measured in blood that shows liver damage when high

is the general amino group transfer enzyme rather than this liver measured form

Compounds

A protein measured in blood that shows liver damage when high

An enzyme in the blood that rises when the liver is damaged

Surface Forms

transaminase singular
transaminases plural

Morphology

transaminase = transaminate (transparent) = trans + amin + ase

Formed by adding the enzyme-forming suffix '-ase' to the verb 'transaminate', following a regular biochemical word-formation pattern.

Etymology

Transaminase breaks into trans- meaning 'across', amine meaning 'an amino group', and the enzyme ending -ase, the same ending as in lactase. So a transaminase is an enzyme that moves an amino group 'across' from one molecule to another, which is why it helps change amino acids.