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immunostaining

immunostaining

1 7.8
A lab method that uses antibodies to show where specific proteins are in cells or tissue
  • noun
  • /ˌɪmjunəˈsteɪnɪŋ/
  • Specialized
translation icon : inmunotinción
  • The researcher used immunostaining to visualize the protein patterns in the tissue samples.
  • positive immunostaining

Examples

  • In this study, 63% of the tumors showed positive immunostaining for p53.

    Academic text (1995)
  • A high degree of PCNA expression on immunostaining has been reported to indicate an aggressive tumor.

    Academic text (2008)
  • Of note, immunostaining for vimentin is negative.

    Academic text (2005)
  • Keywords: Nervous System tumors; histochemical immunostaining

    Academic text (2007)
  • Immunostaining was negative for all antibodies to inflammatory markers.

    Academic text (2015)
  • TUNEL and active caspase-3 immunostaining were used to detect germ cell apoptosis.

    Blog text (23)
  • Dispersion was recorded by time-lapse microscopy. Immunostaining and phalloidin staining.

    Academic text (2018)
  • Untreated cells were also stained with corresponding antibodies to confirm that during immunostaining, the detected signal in the differentiated cells was not due to background auto-fluorescence.

    Academic text (2018)
  • In the controls, the distribution of positive PCNA immunostaining was predominantly located near the basal cell layer of the tumor cords, whereas the BSCC specimens featured diffusely spread tumor islands.

    Academic text (2008)
  • Young's modulus (in Pa) for each gel was determined by AFM, and functionalization was checked by immunostaining against fibronectin (Extended Data Fig. 2km).

    Academic text (2018)

Synonyms

immunohistochemistry
vsimmunostaining
  • Specialized
1 9.0

A laboratory method that finds specific proteins in tissue using marked antibodies

is the broader antibody detection method often creating a visible colored pattern
immunoassay
vsimmunostaining
  • Specialized
1 7.2

A lab test that uses antibodies to find or measure proteins in samples like blood

focuses on detecting proteins in cells or tissues with visible color not just measurement
immunofluorescence
vsimmunostaining
  • Specialized
1 9.6

A lab method that uses glowing antibodies to show specific proteins in cells or tissue

often uses visible color rather than only fluorescence
indirect immunofluorescence
vsimmunostaining
  • Specialized
8.2

A lab method using a first antibody and a glowing second antibody to show targets under a special microscope

can detect proteins without requiring a secondary labeled antibody
immunochemical assay
vsimmunostaining
  • Specialized
6.6

A lab test that uses antibodies to find or measure proteins in body samples

targets visual detection in cells or tissues rather than only measurement

Surface Forms

Morphology

immunostaining = immunostain (semi-transparent) = immuno + stain + ing

The verb 'immunostain' plus the gerundive '-ing' forms 'immunostaining' in a regular way.

Etymology

Immunostaining combines immuno- from immune, meaning 'protected' or the body's defence, and staining from stain, meaning 'to color'. So immunostaining is a way of 'coloring' cells with immune tools like antibodies to show where specific proteins are.