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immunohistochemistry

immunohistochemistry

1 9.0
A laboratory method that finds specific proteins in tissue using marked antibodies
  • noun
  • /ˌɪmjuːnoʊˌhɪstəˈkɛmɪstri/
  • Specialized
translation icon : inmunohistoquímica
  • Most tumor cells express myoepithelial differentiation on either immunohistochemistry or electron microscopy.
  • immunohistochemistry staining
  • immunohistochemistry shows cytokeratin
  • immunohistochemistry was positive

Examples

  • Results of estrogen receptor and c-erbB-2 status using immunohistochemistry were documented.

    Academic text (2007)
  • Tissue sections were first subjected to two-color immunohistochemistry with two different specific antibodies.

    Academic text (2003)
  • The results of the histological examination, including immunohistochemistry, were also recorded.

    Academic text (2007)
  • Strong positivity was also observed on immunohistochemistry for CD68.

    Academic text (2003)
  • APHIS had already used the "gold standard" diagnostic immunohistochemistry test, which was originally developed by ARS.

    Academic text (2004)
  • Application of ancillary techniques like immunohistochemistry and flow cytometry then becomes imperative.

    Academic text (2007)
  • Therefore, diagnosis requires a high index of suspicion, an adequate amount of biopsy material, and immunohistochemistry.

    Academic text (2006)
  • All images were acquired and quantified in a blinded fashion. Immunohistochemistry was performed on free-floating sections following standard procedures.

    Academic text (2018)
  • Sinonasal lymphomas are uncommon malignancies. They are difficult to differentiate from carcinomas, and immunohistochemistry is needed to make the diagnosis.

    Academic text (2006)
  • The researcher used immunohistochemistry to identify the specific proteins in the cancerous tissue sample.

Synonyms

immunoassay
vsimmunohistochemistry
  • Specialized
1 7.2

A lab test that uses antibodies to find or measure proteins in samples like blood

focuses on visually detecting antigens in tissue using labeled antibodies
immunofluorescence
vsimmunohistochemistry
  • Specialized
1 9.6

A lab method that uses glowing antibodies to show specific proteins in cells or tissue

also allows enzyme tags, not limited to fluorescent dyes
immunostaining
vsimmunohistochemistry
  • Specialized
1 7.8

A lab method that uses antibodies to show where specific proteins are in cells or tissue

often uses fluorescent dyes or enzymes as alternative markers
indirect immunofluorescence
vsimmunohistochemistry
  • Specialized
8.2

A lab method using a first antibody and a glowing second antibody to show targets under a special microscope

uses antibodies directly tagged or enzyme labels rather than only secondary fluorescent steps
immunochemical assay
vsimmunohistochemistry
  • Specialized
6.6

A lab test that uses antibodies to find or measure proteins in body samples

is used to detect antigens visually in tissue samples using labeled antibodies

How Sensitive

immunochemical assay
  • Specialized
6.6
bioassay
  • Specialized
1 8.7
immunohistochemistry
  • Specialized
1 9.0
preclinical test
  • Specialized
5.6

Surface Forms

Morphology

immunohistochemistry = histochemistry (opaque) = immuno + histo + chemistry

The term is a specialist technical formation ('immuno-' + 'histochemistry'); the combining forms are domain-specific and not readily interpretable by an average B1 learner.

Etymology

Immunohistochemistry comes from three parts: immuno- meaning 'immune' or 'defense', histo- meaning 'tissue', and chemistry meaning 'chemical methods'. So, immunohistochemistry is a method that uses the body's immune tools and chemical tags to find and show specific things in tissue samples, which is why doctors and scientists use it to spot disease.