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Glite Dictionary
phase I

phase I

2 4.3
The first stage of a medical test with a few people to check safety and the right drug amount
  • noun
  • /feɪz aɪ/
  • Specialized
translation icon : fase I
  • Although Phase I trials come partnered with high risk, they also bring hope.
  • Phase I study
  • phase I protocol
  • Phase I trials

Examples

  • With the successful Phase I completion of the NSF grant, the commercial prototype of iMobot has been developed.

    Academic text (2011)

  • The mean hospital stay after phase I surgery was 2.1 days.

    Academic text (1999)

  • Some patients in Phase I studies may experience a temporary or extended reprieve from their symptoms.

    Academic text (2001)

  • In 1992, we reported a cure rate of 61% following phase I surgery.

    Academic text (1999)

  • "The main focus of Phase I is to ensure that the systems can operate reliably," Homitz said.

    Academic text (2009)

  • Depending on the severity of OSAS, the success rate of phase I surgery ranges from 42% to 78%.

    Academic text (1999)

  • The implementation of Phase I enhancements signified tremendous growth and progress within Sacramento County's Retail Food Protection Program.

    Academic text (2009)

  • The primary objective of this Phase I clinical trial is to establish a dosage that is safe.

  • In light of these positive results, the authors now intend to progress to Phase I human clinical trials.

  • Some patients in Phase I studies may experience a temporary or extended reprieve from their symptoms.

Synonyms

clinical trial
vsphase I
  • Specialized
67 3.9

A controlled test with people to see if a new medicine is safe and works

is limited to the initial small-stage focus on safety and dosage limits
phase I clinical trial
vsphase I
  • Specialized
1 4.3

The first test of a new medicine on a small group to check safety, side effects, and safe dose

has identical meaning but is the longer, more explicit form

How Advanced

phase IV
  • Specialized
6.0
phase III
  • Specialized
2 3.7
phase II
  • Specialized
2 4.7
phase I
  • Specialized
2 4.3
preclinical test
  • Specialized
5.6

Surface Forms

phase I singular
phase Is plural

Morphology

phase + I

The noun 'phase' clearly means a stage, and the capital letter 'I' is conventionally read as the Roman numeral for one, so a learner who recognises that convention can infer 'phase I' = 'first stage'. However, the specialized clinical-trial implications of Phase I (small-sample safety/tolerability testing) are domain-specific and not derivable from the parts, and some learners may be uncertain whether 'I' is a numeral or the pronoun, so the meaning is only partially predictable.

Etymology

Phase I comes from using phase for a stage and I to mean 'one' or 'first'. In medicine it is the name for the 'first' small test of a new drug with a few people to check 'safety' and the right 'dose', so the name explains its current meaning.