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Glite Dictionary
phase IV

phase IV

6.0
A stage after approval that monitors a drug's long-term effects in many patients
  • noun
  • /feɪz fɔr/
  • Specialized
translation icon : fase IV
  • In Phase IV trials, researchers monitor the long-term effects of a drug on a larger patient population.
  • the beginning of phase IV

Examples

  • Phase IV is characterized as post-approval studies and usually continues as long as the product is in the market.

    Academic text (2003)

  • While the medical literature calls for expanded Phase IV trials, the sources of funding for such trials are not clear.

    Academic text (2016)

  • Due to the ultimate failure in Phase II, no Phase IV testing could be conducted on Specimen 5.

    Academic text (2016)

  • Medical professionals often emphasize the importance of Phase IV studies to ensure the ongoing safety of approved medications.

  • Phase IV of a drug trial is essential for identifying any adverse effects that may arise after a drug is released to the public.

Synonyms

phase IV clinical trial
vsphase IV
  • Specialized
5.1

A study done after a drug is approved to check its safety and how well it works in many people

is the shorter name for the same postapproval monitoring stage

How Advanced

phase IV
  • Specialized
6.0
phase III
  • Specialized
2 3.7
phase II
  • Specialized
2 4.7
phase I
  • Specialized
2 4.3
preclinical test
  • Specialized
5.6

Surface Forms

phase IV singular
phase IVs plural

Morphology

phase + IV

The phrase composition is literally 'phase' + 'IV' so a learner who knows both words can infer it denotes the fourth stage of a process. However, the conventional, domain-specific sense in clinical trials (post-approval, post-marketing surveillance with specific regulatory implications) is not predictable from the constituents alone, so full meaning requires prior exposure or background knowledge.

Etymology

The term phase IV names the fourth step in drug testing: phase means a step and IV is the number four. After a drug is 'approved', phase IV is the step when doctors watch many patients to find 'long-term effects' and rare side effects.