Skip to main content
antithrombin

antithrombin

7.0
A protein that helps stop blood clots by blocking some blood proteins
  • noun
  • /ˌæntiˈθrɑːmbɪn/
  • Specialized
translation icon : antitrombina
  • Screening tests for hypercoagulability included normal levels of serum fibrinogen, d-dimers, protein C and S, antithrombin III, but positive antiphospholipid antibodies.
  • antithrombin deficiency
  • antithrombin III
  • antithrombin complex

Examples

  • LMWH is an anticoagulant that works by enhancing the effects of antithrombin.

    Academic text (2012)
  • The risks were greatest for women with antithrombin deficiency and for those with combined defects.

    Academic text (1999)
  • Thrombin-antithrombin complex peaked after 15 minutes of infusion and thereafter began to taper off.

    Academic text (2002)
  • Women with familial thrombophilia, especially those with combined defects or antithrombin deficiency, have an increased risk of fetal loss, particularly stillbirth.

    Academic text (1999)
  • Antithrombin inhibits factors in the coagulation cascade, including factor Ha (thrombin) and factor Xa.

    Academic text (2012)
  • The greatly increased risk of stillbirth in women with deficiencies of antithrombin, protein C, and protein S strongly suggests the possibility of uteroplacental insufficiency as a causative factor.

    Academic text (1999)
  • Antithrombin plays a crucial role in preventing blood clots by inhibiting certain enzymes in the blood.

  • Doctors often prescribe antithrombin to patients at high risk of developing blood clots during surgery.

  • The patient's test results showed a low level of antithrombin, indicating a higher risk for clotting disorders.

Synonyms

anticoagulant
vsantithrombin
  • Specialized
8 5.6

A medicine that slows or stops blood from forming clots

is specifically a protein or medicine that stops certain enzymes
anticoagulant medication
vsantithrombin
  • Specialized
4.2

A medicine that stops or slows blood from forming clots

stops certain enzymes to prevent clots directly
decoagulant
vsantithrombin
  • Specialized
8.7

A substance that stops or slows blood from forming clots

is the protein form that prevents clots by stopping enzymes

Surface Forms

antithrombin singular
antithrombins plural

Morphology

antithrombin = thrombin (semi-transparent) = anti + thrombin

The word is built transparently from 'anti-' plus 'thrombin', but the specialized biochemical reference may not be fully obvious to learners who do not already know 'thrombin'.

Etymology

Antithrombin has three parts: anti- meaning 'against', as in antibiotic, thromb- meaning 'clot', and the protein ending -in, as in insulin. So it is a protein that works 'against clots', which is why it helps prevent blood clots.