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thrombin

thrombin

1 8.0
A protein in blood that helps form clots
  • noun
  • /ˈθrɑːmbɪn/
  • Specialized
translation icon : trombina
  • Dabigatran acts on the coagulation cascade by directly inhibiting the action of thrombin.
  • thrombin inhibitor
  • thrombin-antithrombin complex
  • thrombin-antithrombin

Examples

  • Factor Ha (thrombin) turns fibrinogen into fibrin, and factor Xa turns prothrombin into thrombin.

    Academic text (2015)
  • Antithrombin inhibits factors in the coagulation cascade, including factor Ha (thrombin) and factor Xa.

    Academic text (2012)
  • The scientists then passed the variants through a chromatography column to which human thrombin was attached.

    Academic text (1993)
  • Clipped out, this short sequence also bound to thrombin with high affinity.

    Academic text (1993)
  • The one-in-a-million molecule that bound to the thrombin in the column was made to reproduce.

    Academic text (1993)
  • Thrombin-antithrombin complex peaked after 15 minutes of infusion and thereafter began to taper off.

    Academic text (2002)
  • After the initial generation of thrombin by islet-expressed TF, thrombin-activated platelets start to bind to the islet surface.

    Academic text (2002)
  • One component contains fibrinogen, aprotinin, and/or factor XIII, and the other is made up of human thrombin dissolved in a calcium chloride solution.

    Academic text (2006)
  • IBMIR occurs in clinical islet transplantation, as shown by an increase in concentrations of thrombin-antithrombin complex immediately after islet infusion.

    Academic text (2002)
  • The scientists then passed the variants through a chromatography column to which human thrombin was attached.

Surface Forms

thrombin singular
thrombins plural

Morphology

thrombin = thrombus (opaque) = thromb + in

Formed by adding the protein-forming suffix '-in' to the medical root 'thromb-/thrombus'; this is a technical formation and not transparent to an average B1 learner.

Etymology

Thrombin comes from the Greek root thromb- meaning 'clot' and the ending -in that names many proteins. So thrombin is a blood protein that helps form 'clots', which explains its role in blood clotting.