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suppressor

suppressor

4 8.8
A gene that reduces the effects of another gene, often a harmful change
  • noun
  • /səˈprɛsər/
  • Specialized
translation icon : gen supresor
  • Compelling evidence indicates that p27 is a tumor suppressor protein.
  • suppressor gene
  • tumor suppressor
  • p53 tumor suppressor

Who can tell me where the tumor suppressors are in this pathway?

Examples

  • Certain invasion tumor suppressor genes have been implicated.

    Academic text (2007)
  • OK, so I've told you about oncogenes and tumor suppressor genes.

  • Who can tell me where the tumor suppressors are in this pathway?

  • The numerous experimental data suggest that a threshold is necessary for allowing the CKI to act as a tumor suppressor protein.

    Academic text (2017)
  • For example, injecting tumor suppressor genes can slow some tumors.

    Academic text (2012)
  • Molecular genetics has provided evidence that loss or inactivation of tumor suppressor genes is an important step in carcinogenesis.

    Academic text (1995)
  • Both the activation of oncogenes and the inactivation of tumor suppressor proteins are involved in these pathways.

    Academic text (2003)
  • Two mutations in the p53 tumor suppressor gene have been shown by different methods in human laryngeal carcinoma.

    Academic text (1995)
  • The tumor suppressor protein programmed cell death 4 (PDCD4) is an independently validated target of miR-21 89.

    Academic text (2016)
  • Tumor suppressor genes play a crucial role in controlling cell growth and preventing cancer.

Synonyms

repressor
vssuppressor
  • Specialized
1 9.0

A substance, gene, or protein that attaches to DNA to stop a gene from working

is specifically a gene that reduces another gene's phenotypic expression
suppressor gene
vssuppressor
  • Specialized
1 5.6

A gene that reduces the effect of a harmful mutated gene

has identical meaning but appears as the compound form that includes gene
suppresser
vssuppressor
  • Specialized
8.8

A gene that stops another gene from showing its effect

has identical biological meaning but uses an alternate spelling
suppresser gene
vssuppressor
  • Specialized
7.1

A gene that stops or reduces another gene from working

has identical meaning but shows a variant spelling combined with gene
epistatic gene
vssuppressor
  • Specialized
9.6

A gene that hides the effect of another gene so a trait does not appear

focuses on masking across loci while the key targets general trait suppression
repressor gene
vssuppressor
  • Specialized
7.2

A gene that makes a protein that stops other genes from turning on

acts on visible trait outcomes rather than directly blocking transcription

Antonyms

activator
  • Specialized
1 6.3

A substance that increases enzyme activity or makes genes produce more protein

Compounds

tumor suppressor gene
  • Specialized
2 4.0

A gene that controls cell division to stop tumors forming

suppressor gene
  • Specialized
1 5.6

A gene that reduces the effect of a harmful mutated gene

surge suppressor
  • Specialized
5.0

A device that protects things like computers and TVs from sudden rises in electricity

spike suppressor
  • Specialized
6.3

A device that protects electronic equipment from sudden power surges

Surface Forms

suppressor singular
suppressors plural

Morphology

suppressor = suppress (semi-transparent) = suppress + or

While the formation is clear, the specific genetic context may not be immediately obvious to all learners.

Etymology

Suppressor comes from the Latin parts sup- 'under' and press 'to push', so it literally means 'to push down'. In genetics a suppressor is a gene that 'pushes down' the effect of another gene, which is why it can hide or reduce a mutation's visible traits.