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streptokinase

streptokinase

1 8.4
A medicine made by bacteria that breaks up blood clots
  • noun
  • /ˌstrɛp.təˈkaɪ.neɪs/
  • Specialized
translation icon : estreptokinasa
  • Streptokinase (Kabi, Sweden) 1.5 MU was infused intravenously over 1 hour in 1 dL physiological saline.
  • streptokinase and aspirin
  • streptokinase alone
  • streptokinase-treated patients

Examples

  • The doctor administered streptokinase to dissolve the blood clot in the patient's pulmonary artery.

  • However, patients allocated to streptokinase had a higher 10-day case fatality than controls (27% vs 12%, OR 2.7, 95% CI 1.7-4.3).

    Academic text (1995)
  • The best way to express this is to look at the case of the anticoagulant streptokinase.

    Academic text (2006)
  • However, it took more than 10 years before streptokinase infusion became routinely accepted therapy.

    Academic text (2006)
  • Non-fatal anaphylactic shock developed in one patient treated with streptokinase.

    Academic text (1995)
  • Patients were randomly assigned in equal proportion to four treatment groups: streptokinase alone, aspirin alone, both, or neither.

    Academic text (1995)
  • The present study provides evidence of a higher risk of 10-day case fatality with streptokinase plus aspirin than with streptokinase alone.

    Academic text (1995)
  • In 1982, administration of streptokinase was shown to improve survival in patients undergoing an acute myocardial infarction.

    Academic text (2006)
  • Of the 83 deaths in the streptokinase-treated patients, 63 were attributed to cerebral causes, 9 to cardiac causes, and 11 to other causes.

    Academic text (1995)
  • A trial was conducted to determine whether, separately or together, streptokinase and aspirin have clinical benefits in acute ischaemic stroke similar to those in acute myocardial infarction.

    Academic text (1995)

Synonyms

urokinase
vsstreptokinase
  • Specialized
1 9.9

A natural protein made in the kidneys that helps break down blood clots

is produced by bacteria and used therapeutically to dissolve clots
thrombolytic agent
vsstreptokinase
  • Specialized
6.2

A drug that breaks up blood clots to restore blood flow during a heart attack or stroke

is a specific bacterial enzyme used to dissolve clots in heart and lungs
tissue plasminogen activator
vsstreptokinase
  • Specialized
4.5

A medicine that breaks up blood clots to treat heart attacks and strokes

is produced by bacteria rather than being a human protein
plasmin
vsstreptokinase
  • Specialized
8.6

A protein in the blood that breaks down blood clots

is a bacterial treatment that causes or increases that natural clot breakdown

Surface Forms

streptokinase singular

Morphology

streptokinase = kinase (opaque) = strepto + kinase

The formation uses the technical combining form 'strepto-' (referring to streptococci) attached to the biomedical term 'kinase'; this is specialized and not derivable by an average B1 learner.

Etymology

Streptokinase comes from the bacteria name strepto- meaning 'twisted' and the part -kinase from a root meaning 'to move', as in kinetic. So streptokinase is an enzyme made by strep bacteria that 'moves' chemicals in the blood to help break up clots, which is why doctors use it to dissolve clots.