tumorigenesis
1
8.2
- noun
- /ˌtjuːmərɪˈdʒɛnɪsɪs/
- Specialized
:
tumorogénesis
- Understanding the early stages of tumorigenesis is crucial for developing effective cancer prevention strategies.
Examples
-
Epigenetic regulation of gene expression plays a key role in tumorigenesis.
Academic text (2017) -
Deregulation of this histone modification can lead to epigenetic silencing of tumor suppressor genes, thus leading to tumorigenesis.
Academic text (2017) -
Emerging Role of Long Non-Coding RNA in Tumorigenesis
Blog text (18) -
Several studies have shown that a high expression of ephrins may be associated with an increased potential for tumorigenesis, including growth and metastasis.
Academic text (2003) -
Specifically, Pim-1 is thought to promote inflammation-induced tumorigenesis and promote cancer cell survival during chemotherapy and radiation treatment.
Academic text (2017) -
Collectively, these reports have suggested that aberrant T-UCR expression may have a yet undetermined biological role in tumorigenesis.
Blog text (18) -
We must continue our research efforts aimed at increasing basic understanding of the mechanisms of tumorigenesis and metastasis while encouraging recruitment into important clinical trials aimed at answering some of the critical questions.
Academic text (1993) -
Our results reinforce this link and suggest that modulation of cell plasticity may be a key mechanism by which injury sensitizes normal cells to tumorigenesis.
Academic text (2017) -
Collectively, these observations suggest that lncRNA-mediated silencing of tumor suppressor genes may be a major mechanism driving tumorigenesis.
Blog text (18) -
Vasorin (VASN) is a transmembrane protein with a pivotal role in tumorigenesis and vasculogenesis.
Academic text (2017)
Synonyms
1
9.4
Abnormal, uncontrolled cell growth that forms a lump or tumor
1
7.5
The process by which normal cells change into cancer cells
Normal tissue changes into cancer cells
A process in which normal cells change into cancer cells
Surface Forms
Morphology
Etymology
Tumorigenesis joins tumor (a swelling or growth) and genesis (a word meaning 'birth' or 'origin'), the same root you see in generate. So tumorigenesis means the 'birth' or forming of a tumor, which explains why it names the process by which tumors develop.