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carcinogenesis

carcinogenesis

1 7.5
The process by which normal cells change into cancer cells
  • noun
  • /ˌkɑːrsɪnoʊˈdʒɛnɪsɪs/
  • Specialized
translation icon : carcinogénesis
  • In addition, we demonstrated that reactive oxygen species are an upstream event of the miR-199a-5p/HIF-1/COX-2 pathway in arsenic-induced carcinogenesis.
  • arsenic-induced carcinogenesis
  • gastric carcinogenesis
  • toxicity and carcinogenesis

Examples

  • Research shows that exposure to certain chemicals can trigger carcinogenesis in healthy cells.

  • Weitzman SA, Gordon LI. 1990. Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis. Blood 76:655-663.

    Academic text (2012)
  • These findings inform esophageal carcinogenesis and provide testable candidates for future functional studies.

    Academic text (2018)
  • Molecular genetics has provided evidence that loss or inactivation of tumor suppressor genes is an important step in carcinogenesis.

    Academic text (1995)
  • Substances of concern in the American Trader oil spill were crude oil for non-carcinogenic health effects and PAH for carcinogenesis.

    Academic text (1994)
  • High concentrations of pregnancy oestrogens may have an important role in breast carcinogenesis, but other pregnancy hormones or intrauterine factors may also be involved.

    Academic text (1996)
  • Additional evidence of a viral link to carcinogenesis was provided by the discovery that serum antibodies to HSV are elevated in patients with head and neck cancer.

    Academic text (2006)
  • Based on these observations, HBV was identified as the major causal factor in hepatocellular carcinogenesis (n8).

    Academic text (1991)
  • We considered the effects from the germline and somatic levels to suggest several potential determinants of the somatic mutational processes and provide insights into esophageal carcinogenesis and inform the future diagnosis and therapy.

    Academic text (2018)
  • Aberrant cell surface glycosylation is not exclusive to the initial gastric carcinogenesis stages, being also observed in pre-malignant conditions and constituting a marked feature of gastric carcinoma cells 14.

    Academic text (2016)

Synonyms

tumorigenesis
vscarcinogenesis
  • Specialized
1 8.2

Cells grow in an abnormal way and form a lump in the body

concerns direct transformation of normal cells into cancer cells
oncogenesis
vscarcinogenesis
  • Specialized
9.3

A process in which normal cells change into cancer cells

has identical meaning but is an alternative scientific term
cancerization
vscarcinogenesis
  • Specialized
9.9

Normal tissue changes into cancer cells

focuses on change at the cellular level rather than whole tissue

Surface Forms

carcinogenesis singular

Morphology

carcinogenesis = carcino + genesis (semi-transparent) = carcino + genesis

The components 'carcino' and 'genesis' are clear, but the specific biological process meaning is specialized.

Etymology

Carcinogenesis comes from Greek parts carcino- meaning 'crab' and -genesis meaning 'birth' or 'origin', because ancient doctors called tumors 'crabs'. So carcinogenesis is the 'birth' or start of cancer, the process when normal cells become cancer cells.