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proinflammatory

proinflammatory

1 7.4
Causing swelling, pain, or redness in body tissues
  • adjective
  • /ˌproʊɪnˈflæməˌtɔri/
  • Specialized
translation icon : proinflamatorio
  • Thus, the superficially straightforward proinflammatory circuit has given way to an intricate, highly ordered, yet poorly understood network of feedforward and feedback mechanisms working in a sequential and concurrent fashion, impacting immunity at all levels.
  • proinflammatory cytokines
  • proinflammatory markers
  • proinflammatory mediators

Examples

  • Previous work has shown that proinflammatory cytokines, including IL-6 and CRP, tend to decrease over the course of antidepressant treatment. 40-48

    Academic text (2013)
  • Although some studies have suggested that antidepressant use may promote proinflammatory cytokine production, 46 others have produced conflicting results, indicating no change in inflammatory biomarkers over the course of antidepressant treatment.

    Academic text (2013)
  • Consistent with our findings, several studies have found that elevated depressive symptoms are associated with elevated CRP and proinflammatory cytokines.

    Academic text (2013)
  • Remarkably, ruxolitinib significantly down-modulated the high levels of proinflammatory cytokines present in the circulation in myelofibrosis patients.

    Blog text (28)
  • Additionally, there was no evidence of proangiogenic or proinflammatory marker concentration with immunohistochemical analysis, thereby confirming preserved tissue viability.

    Academic text (2015)
  • Furthermore, the lack of significant increases in proinflammatory and/or proangiogenic markers (i.e., gene expression) emphasizes the lack of significant or long-lasting vascular changes.

    Academic text (2015)
  • Excess adipose tissue may increase proinflammatory cytokines, promote ectopic fat deposition, and disrupt mitochondrial function (Eckel et al., 2011).

    Academic text (2016)
  • The oxidation of IgG significantly changes the immunoreactivity and specificity of IgG fractions. Oxidized immunoglobulins have autoimmune and proinflammatory activity.

    Academic text (2017)
  • However, the lack of ICAM immunohistochemistry evidence and the failure to identify any statistically significant increase in proinflammatory markers (via PCR) indicate that the inflammation is both transient and mild.

    Academic text (2015)
  • Consuming too much sugar can create a proinflammatory response in the body, leading to various health issues.

Synonyms

inflammatory
vsproinflammatory
  • Specialized
21 6.8

Causing swelling, redness, and pain in a part of the body

focuses on causing or promoting inflammation rather than describing an inflamed state
pro-inflammatory
vsproinflammatory
  • Specialized
6.2

Causing parts of the body to become red, hot, or swollen

is the same meaning but written without a hyphen in modern usage

Antonyms

anti-inflammatory
  • Specialized
1 3.5

A medicine that reduces swelling and pain in the body

How Inflammatory

proinflammatory
  • Specialized
1 7.4
inflammatory
  • Specialized
21 6.8
anti-inflammatory
  • Specialized
1 3.5

Surface Forms

proinflammatory positive

Morphology

proinflammatory = inflammatory (semi-transparent) = pro + inflame + atory

The prefix 'pro-' straightforwardly adds the meaning 'promoting' to 'inflammatory', yielding 'promoting inflammation'.

Etymology

Proinflammatory combines pro- meaning 'for' or 'promoting' and inflammatory from 'inflame', which means 'to set on fire'. So a proinflammatory thing helps start or make inflammation, like a small 'fire' of swelling and pain in the body.