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polygenic disease

polygenic disease

6.5
A disease passed from parents caused by several genes acting together
  • noun
  • /ˌpɒlɪˈdʒɛnɪk dɪˈziːz/
  • Specialized
translation icon : enfermedad poligénica
  • Glaucoma is a complex disease, which may be a polygenic disease rather than a monogenic disease.

Examples

  • Diabetes is a common polygenic disease that results from the interaction of multiple genes and environmental factors.

  • Research shows that heart disease can be a polygenic disease, influenced by various genes working together.

  • Many mental health disorders, such as schizophrenia, are classified as polygenic diseases due to their genetic complexity.

Synonyms

genetic disease
vspolygenic disease
  • Specialized
12 3.5

A health problem caused by a change in a person's genes that can be passed from parents

is limited to conditions caused specifically by many genes acting together
genetic disorder
vspolygenic disease
  • Specialized
9 4.2

A health problem caused by changes in a person's genes that parents pass on

focuses on several genes acting together rather than a single gene
genetic abnormality
vspolygenic disease
  • Specialized
3 4.6

A change in a person's genes that causes a disease

highlights combined effects of many genes rather than a single gene
inherited disease
vspolygenic disease
  • Specialized
2 3.0

A disease passed from parents to their children through genes

is about conditions caused by many genes acting together rather than single ones
hereditary disease
vspolygenic disease
  • Specialized
1 3.9

A disease passed from parents to children through genes

uses the combined gene effect as cause rather than simple inheritance
hereditary condition
vspolygenic disease
  • Specialized
1 4.0

A health problem parents can pass to their children through genes

specifies many genes acting together as the cause instead of single gene
inherited disorder
vspolygenic disease
  • Specialized
1 4.2

A disease parents pass to their children in their genes

emphasizes multiple genes combining to cause the condition not one gene
polygenic disorder
vspolygenic disease
  • Specialized
7.0

An inherited disease caused by many genes, for example high blood pressure or type 2 diabetes

is the same concept but uses a different medical label

How Polygenic

polygenic disease
  • Specialized
6.5
monogenic disease
  • Specialized
5.8

Surface Forms

Morphology

polygenic + disease

The adjective 'polygenic' (determined by multiple genes) plus the noun 'disease' composes directly to mean a disease caused by multiple genes. This is a straightforward adjective+noun composition following regular semantic rules, so a B1 learner who knows both constituents would be able to infer the meaning.

Etymology

The term polygenic disease comes from the idea that many small changes in genes add up like drops filling a bucket until it overflows. So it means a disease 'caused by many genes' rather than one gene.