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Glite Dictionary
polygenic

polygenic

1 9.0
A trait when several genes work together instead of one gene
  • adjective
  • /ˌpɒlɪˈdʒɛnɪk/
  • Specialized
translation icon : poligénico
  • There is a possible polygenic interaction among MYOC, OPTN, and apolipoprotein E (APOE).
  • polygenic effect
  • genes (i.e., polygenic)

And what if you have a high polygenic score?

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Examples

  • Glaucoma is a complex disease, which may be a polygenic disease rather than a monogenic disease.

    Academic text (2018)

  • And so there are hundreds, thousands of polygenic risk scores for lots and lots of different diseases.

    StarTalk

  • Diabetes mellitus type 2 has a strong polygenic genetic predisposition, more than type 1.

    Blog text (20)

  • F2 populations in the crosses were normally distributed between the ranges of respective parents during the two years, which indicated the polygenic nature of the trait in wheat.

    Academic text (2014)

  • Our results indicate that even for a highly complex trait such as standing height, the use of polygenic prediction coupled with big data can close a sizable fraction of the gap between trait heritability and prediction R-sq.

    Academic text (2017)

  • Lupus is considered a polygenic disease because there are likely many genes involved in its development.

  • Many physical traits, such as skin color and height, are polygenic, meaning they are influenced by multiple genes working together.

  • Diabetes mellitus type 2 has a strong polygenic genetic predisposition, more than type 1.

Synonyms

polygenetic
vspolygenic
  • Specialized
9.4

Caused by many genes working together

shows direct control by several genes rather than a single one

Compounds

polygenic disease
  • Specialized
6.5

A disease passed from parents caused by several genes acting together

polygenic disorder
  • Specialized
7.0

An inherited disease caused by many genes, for example high blood pressure or type 2 diabetes

How Polygenic

polygenic
  • Specialized
1 9.0
monogenic
  • Specialized
8.8

Surface Forms

polygenic positive

Morphology

polygenic = genic (transparent) = poly + gene + ic

The word is transparently built from the prefix 'poly-' meaning 'many' and a gene-related base, so the sense 'involving several genes' is directly recoverable.

Etymology

Polygenic comes from poly- meaning 'many' and gene meaning 'a part that carries traits', so polygenic describes a trait that is controlled by many genes working together.