Skip to main content
monogenic

monogenic

8.8
A trait or disease that a single gene causes
  • adjective
  • /ˌmɒnəˈdʒɛnɪk/
  • Specialized
translation icon : monogénico
  • Glaucoma is often studied as a polygenic condition, while other conditions are clearly monogenic diseases.

We characterize as monogenic diseases, diseases that until yesterday we thought were acquired diseases.

Examples

  • Glaucoma is a complex disease, which may be a polygenic disease rather than a monogenic disease.

    Academic text (2018)
  • Researchers have identified more than 7,000 monogenic disorders that are inherited diseases controlled by a single pair of genes.

  • Thus, the number of monogenic disorders is expected to increase.

    Academic text (2004)
  • We characterize as monogenic diseases, diseases that until yesterday we thought were acquired diseases.

  • Monogenic resistance due to a series of Rps genes has been providing reasonable protection to the soybean crop against the pathogen over the last four decades.

    Blog text (27)
  • The discovery of new monogenic causes of diseases has advanced our understanding of genetic inheritance.

Antonyms

polygenic
  • Specialized
1 9.0

A trait when several genes work together instead of one gene

Compounds

monogenic disease
  • Specialized
5.8

A disease caused by a change in a single gene that a person inherits

monogenic disorder
  • Specialized
8.0

A disease that happens when one gene changes and parents pass that change to their child

How Polygenic

polygenetic
  • Specialized
9.4
monogenic
  • Specialized
8.8

Surface Forms

monogenic positive

Morphology

monogenic = genic (semi-transparent) = mono + gen + ic

The word is built from the scientific prefix mono- plus genic, but the specialized biological sense is not fully transparent to an average learner.

Etymology

Monogenic comes from mono- 'single' and -genic 'from a gene', the same root you see in genetic. So a monogenic trait or disease is one that is caused or controlled by just a single gene.