Skip to main content
polygenic disorder

polygenic disorder

7.0
An inherited disease caused by many genes, for example high blood pressure or type 2 diabetes
  • noun
  • /ˌpɒlɪˈdʒɛnɪk dɪsˈɔːrdər/
  • Specialized
translation icon : trastorno poligénico
  • Type 2 diabetes is a common polygenic disorder influenced by several genetic and environmental factors.

Examples

  • Unlike single-gene conditions, a polygenic disorder results from the interaction of multiple genes.

  • Many cases of high blood pressure are considered to be a polygenic disorder.

  • A polygenic disorder can affect multiple systems in the body.

  • Many researchers study polygenic disorders to understand their complexity.

  • Conditions like diabetes and hypertension are classified as polygenic disorders because they result from the effects of multiple genes working together.

  • Research has shown that many polygenic disorders, such as asthma, are influenced by both genetic and environmental factors.

  • Understanding polygenic disorders is crucial for developing effective treatment strategies that consider multiple genetic influences.

Synonyms

genetic disease
vspolygenic disorder
  • Specialized
12 3.5

A health problem caused by a change in a person's genes that can be passed from parents

is caused by several genes combining effects rather than a single gene
genetic disorder
vspolygenic disorder
  • Specialized
9 4.2

A health problem caused by changes in a person's genes that parents pass on

is caused by multiple genes acting together rather than one gene
genetic defect
vspolygenic disorder
  • Specialized
6 4.4

A health problem from a change in someone's genes often passed from parents

focuses on combined action of many genes instead of a single gene
genetic abnormality
vspolygenic disorder
  • Specialized
3 4.6

A change in a person's genes that causes a disease

highlights that multiple genes together cause the condition not one
inherited disease
vspolygenic disorder
  • Specialized
2 3.0

A disease passed from parents to their children through genes

specifies that many genes jointly produce the inherited illness not a single gene
hereditary disease
vspolygenic disorder
  • Specialized
1 3.9

A disease passed from parents to children through genes

points out that multiple genes together cause it rather than a single gene
hereditary condition
vspolygenic disorder
  • Specialized
1 4.0

A health problem parents can pass to their children through genes

stresses that many genes combine to cause it instead of one gene
inherited disorder
vspolygenic disorder
  • Specialized
1 4.2

A disease parents pass to their children in their genes

emphasizes combined effects of several genes rather than one gene
polygenic disease
vspolygenic disorder
  • Specialized
6.5

A disease passed from parents caused by several genes acting together

is the same meaning but written with a different phrase

How Polygenic

polygenic disorder
  • Specialized
7.0
monogenic disorder
  • Specialized
8.0

Surface Forms

Morphology

polygenic + disorder

The phrase is directly compositional: 'polygenic' means caused by multiple genes and 'disorder' means a medical condition, so together they denote a condition caused by multiple genes. This follows a standard adjective + noun pattern and is therefore understandable to learners who already know both constituent words.

Etymology

Polygenic disorder names the idea: polygenic means 'many genes' and disorder means 'health problem', so imagine many small genetic changes adding up until they cause illness. That's why it means a condition 'caused by several genes' rather than one.