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germline

germline

1 7.0
Genes and cells in egg or sperm that parents pass to children
  • noun
  • /ˈdʒɜrmˌlaɪn/
  • Specialized
: células germinales
  • Germline mutations can be passed down to future children, potentially affecting their health and development.
  • germline engineering
  • human germline
  • germline cells

So your germline and my germline are set when we were born.

Examples

  • So should we celebrate or condemn this first step into reproductive cell or germline genetic engineering?

    Blog text (30)
  • So your germline and my germline are set when we were born.

  • An interest in barring clinical uses of germline gene editing may well be "an important or substantial" one.

    Academic text (2017)
  • Well, that's because there is a barrier between the genes of the germline cells and behaviors.

  • We can encode those genes taken from some mice into the germline genome.

  • The state could most effectively prevent health, safety, and other concerns about clinical germline gene editing by prohibiting the clinical use of such technology.

    Academic text (2017)
  • The sequencing results showed that several types of mutations have passed through the germline (data not shown).

    Academic text (2017)
  • The next step in disease elimination is to attempt to refine a process known as "human germline engineering" or "human germline modification."

    Academic text (2007)
  • All 249 mutations so far tested were somatic rather than germline mutations.

    Academic text (1991)
  • Germline modification would begin by using IVF to create a single-cell embryo or zygote.

    Academic text (2007)

Synonyms

germ cell
vsgermline
  • Specialized
2 5.8

Cell like a sperm or egg that carries genes to children

includes hereditary genetic material inside those units
reproductive cell
vsgermline
  • Specialized
1 3.4

A cell like a sperm or egg that carries half the genes for a new life

refers to the hereditary genetic material passed across generations, not one individual unit
germplasm
vsgermline
  • Specialized
1 9.3

Seeds, cells, or tissue that carry parents' traits for breeding and conservation

focuses on inherited genetic line inside parents rather than stored breeding samples

Antonyms

somatic cell
  • Specialized
2 4.9

A body cell that is not a sex cell

Surface Forms

germline singular
germlines plural

Morphology

germline = germ + line (semi-transparent) = germ + line

The compound components are clear but the meaning is specialized (referring specifically to reproductive cells or their genetic material), which may not be obvious to general learners.

Etymology

Germline comes from germ meaning 'seed' or 'sprout', the same root as germinate, and line meaning a 'family line'. So the germline is the 'seed line' of eggs and sperm that carry genes to your children.