Skip to main content
epitope

epitope

1 9.9
Part of a viral or bacterial protein that an antibody binds to
  • noun
  • /ˈɛpɪˌtoʊp/
  • Specialized
translation icon : epítopo
  • Monoclonal antibody 4509 inhibits TF activity, and 4503 recognizes a non-functional epitope of TF.
  • T-cell epitopes
  • CTL epitopes
  • helper epitopes

This is now to use these single nanobody fusions that are dependent upon the presence of epitope and to use them as detectors.

Examples

  • In addition, gastric and colorectal tumors present high levels of SLeA and SLeX as terminal epitopes of protein O-glycans, but also of N-glycans and glycolipids.

    Academic text (2016)
  • Further study would be required to determine what epitopes or components of SPf66 are responsible for inducing allergic reactions.

    Academic text (2000)
  • Now, most of the B cells in the body will not have an epitope that she recognizes.

  • The nature and extent of epitope variation in M. tuberculosis strains is unclear.

    Academic text (2013)
  • Neo-antigens might induce antibody-targetable epitopes, but whether this is the case is unclear.

    Academic text (2017)
  • The HIV envelope glycoprotein includes several potent antigenic epitopes capable of eliciting a proliferative response from T cells, even on primary exposure.

    Academic text (1992)
  • Researchers have identified specific epitopes on the virus that trigger strong immune responses.

  • The vaccine was designed to target multiple epitopes of the pathogen to enhance its effectiveness.

  • By studying the epitopes that bind to antibodies, scientists can develop better treatments for infections.

Synonyms

determinant
vsepitope
  • Specialized
1 9.8

The part of an antigen that an antibody binds to

is broader by referring to the binding part not limited to surface areas
antigenic determinant
vsepitope
  • Specialized
8.0

The small part of a germ or protein that an antibody sticks to

is the same idea but expressed with a shorter single word label

Surface Forms

epitope singular
epitopes plural

Etymology

The word epitope comes from Greek parts epi- 'on' and -topos 'place'. You can see epi- in familiar words like epidermis, where it means 'on' the skin. So an epitope is the small 'place on' an antigen or protein where an antibody can attach.