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cholinesterase

cholinesterase

1 9.1
A body enzyme that breaks down acetylcholine in nerves
  • noun
  • /ˌkoʊlɪˈnɛstərˌeɪs/
  • Specialized
: colinesterasa
  • Doctors often measure cholinesterase levels to understand the impact of certain medications on a patient's nervous system.
  • cholinesterase inhibitor
  • cholinesterase activity

Examples

  • MP is a dangerous substance that destroys or damages an enzyme (cholinesterase) essential for the proper working of the nervous systems in humans, animals, and insects.

    Academic text (2000)
  • One applicator mentioned not understanding cholinesterase blood test results.

    Academic text (1994)
  • The pilots' cholinesterase levels could also be tested before the application of organophosphates or carbamates.

    Academic text (2005)
  • Acetylcholine is destroyed rapidly by cholinesterase; therefore, a difference in cholinesterase activity might explain differing responses in the hypercholesterolaemic and control groups.

    Academic text (1992)
  • Thirteen percent of applicators (n=173) reported having blood cholinesterase tests each spring, but only 40% of those individuals had follow-up tests in the fall.

    Academic text (1994)
  • Lander and Lings found that cholinesterase enzyme (ChE) activity decreased as weekly spraying time increased among greenhouse workers.

    Academic text (1994)
  • The cholinesterase enzyme breaks down acetylcholine in the nerve tissues, helping regulate muscle contractions.

  • An abnormal level of cholinesterase can indicate a potential health issue related to nerve function.

Synonyms

acetylcholinesterase
vscholinesterase
  • Specialized
1 9.3

A chemical in the nervous system that breaks down acetylcholine

focuses on producing choline and acetic acid in nerve tissues

Surface Forms

Morphology

cholinesterase = choline + esterase (semi-transparent) = cholin + esterase

The word is transparently composed of the combining form 'cholin-' and 'esterase', but the medical/biochemical meaning requires domain knowledge beyond general B1 vocabulary.

Etymology

Cholinesterase comes from three parts: choline (named from the Greek word for 'bile', as in cholesterol), ester (a type of chemical link), and -ase (a common ending for enzymes, as in lipase). So cholinesterase is an enzyme that 'breaks down' choline-related chemicals like the nerve messenger acetylcholine, which explains its role in nerve tissues.