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ritonavir

ritonavir

1 6.2
A drug used to treat HIV, usually with other medicines
  • noun
  • /rɪˈtɒnɪvɑɪr/
  • Specialized
: ritonavir
  • Chimeric mice were first treated with clemizole alone, and later given a combination of clemizole and ritonavir.
  • lopinavir/ritonavir

Examples

  • AbbVie charges MICs $740 per patient per year for lopinavir/ritonavir (more than twice the price of $231 per patient per year in LDCs); this price has not changed since 2012.

    Academic text (2016)
  • Doctors often prescribe ritonavir alongside other medications to improve treatment outcomes for HIV patients.

  • A price of more than $3,500 per patient per year was quoted for lopinavir/ritonavir in 2014 in Malaysia.

    Academic text (2016)
  • Similarly, its bioavailability increased 20-fold when administered in combination with ritonavir.

    Blog text (19)
  • Approval of these drugs by the US Food and Drug Administration was based on surrogate markers of disease, and for ritonavir, on an improvement in survival.

    Academic text (2000)
  • Ritonavir has been associated with gastrointestinal intolerance and peripheral neuropathy, which has led to poor compliance in some patients.

    Academic text (2000)
  • Although monotherapy and combination therapy have been approved for ritonavir and indinavir, the use of these agents alone and their optimum use in HIV infection have yet to be defined.

    Academic text (2000)
  • At the time of hospital admission, the patient had been taking lopinavir/ritonavir, emtricitavine/tenofovir, doses for pneumocystis prophylaxis, azithromycin, and loperamide for 6 months.

    Academic text (2007)
  • In particular, it was considered important to bring together all the available evidence on the use of certain antiviral drugs (ribavirin, lopinavir, and ritonavir), steroids, and proteins called immunoglobulins, which are found naturally in human blood.

    Blog text (21)
  • In a clinical trial, ritonavir was shown to effectively suppress the HIV virus when combined with other antiretroviral drugs.

Synonyms

protease inhibitor
vsritonavir
  • Specialized
5 5.3

A medicine that stops enzymes from breaking proteins and treats HIV

is a single drug that belongs to this broader class
antiviral drug
vsritonavir
  • Specialized
3 3.7

A medicine that stops viruses from growing in the body

is a specific HIV protease blocker rather than a general antiviral
nelfinavir
vsritonavir
  • Specialized
1 9.6

A drug that helps treat HIV when taken with other HIV medicines

is another specific drug within the same treatment class
Viracept
vsritonavir
  • Specialized
1 9.0

A medicine used with other drugs to treat HIV infection

is the generic drug name rather than the brand
saquinavir
vsritonavir
  • Specialized
1 8.8

A medicine for HIV that stops an enzyme the virus needs

is in the same drug class but is a different specific medication
Crixivan
vsritonavir
  • Specialized
1 9.2

A medicine for HIV that helps stop the virus from multiplying

is the generic drug name rather than the brand
indinavir
vsritonavir
  • Specialized
1 8.4

A medicine used to treat HIV by stopping the virus from making more copies

is in the same drug class but is a different specific medication
Norvir
vsritonavir
  • Specialized
1 7.9

A medicine doctors use with other drugs to treat HIV infection

is the generic drug name rather than a brand name
Invirase
vsritonavir
  • Specialized
1 9.9

A brand name for a medicine that helps stop HIV from making more copies

is the generic drug name rather than the brand

Surface Forms

ritonavir singular
ritonavirs plural

Etymology

Ritonavir is a modern drug name made by scientists. The ending -vir links it to 'virus' and other antiviral names, and the middle part sounds like other HIV drugs such as saquinavir, so the name helps you remember it is an antiretroviral protease inhibitor.