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ritonavir

ritonavir

7.2
A low-dose medicine that raises the blood level of other drugs by slowing their breakdown in the liver
  • noun
  • /rɪˈtɒnɪvɑr/
  • Specialized
: ritonavir
  • They picked a drug called ritonavir, which is known to interfere with a metabolic enzyme that is crucial to the breakdown of many drugs in humans.

Examples

  • Co-administering ritonavir caused clemizole's blood level to increase and to remain elevated for longer than was the case with clemizole alone.

    Blog text (29)
  • As occurred in the chimeric mice, co-administration of ritonavir caused a substantial increase in the blood levels of clemizole in two subjects and a smaller increase in the third subject.

    Blog text (29)
  • Co-administering ritonavir caused clemizole's blood level to increase and to remain elevated for longer than was the case with clemizole alone.

  • As occurred in the chimeric mice, co-administration of ritonavir caused a substantial increase in the blood levels of clemizole in two subjects and a smaller increase in the third subject.

  • They picked a drug called ritonavir, which is known to interfere with a metabolic enzyme that is crucial to the breakdown of many drugs in humans.

Synonyms

Norvir
vsritonavir
  • Specialized
1 7.9

A medicine doctors use with other drugs to treat HIV infection

is used mainly to boost levels of other drugs by inhibiting a liver enzyme

Surface Forms

ritonavir singular
ritonavirs plural

Etymology

Ritonavir does not come from a word meaning 'booster', but the drug became known for a second job as a 'booster' of other medicines. A helpful way to remember this is to think of ritonavir as slowing the body's breaking down of other drugs so it 'raises' their levels, which is why doctors give it in low dose to boost other antivirals.