protease inhibitor
5
5.3
- noun
- /ˈproʊtiˌeɪs ɪnˈhɪbɪtər/
- Specialized
:
inhibidor de proteasa
- If in the next two years the protease inhibitors prove highly successful, then access to treatment will be a big issue at the Geneva meeting in 1998.
- drugs: protease inhibitors
- HIV protease inhibitors
- new protease inhibitors
Examples
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Research has shown that patients on protease inhibitors can experience improved health outcomes over time.
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Development of resistance has been seen with these agents, including cross-resistance to other protease inhibitors.
Academic text (2000) -
Darunavir is the 10th protease inhibitor to be marketed in the United States, and it was approved by the FDA on June 23, 2006.
Blog text (19) -
Natural sources of protease inhibitors exist and have varying degrees of specificity toward protease enzymes.
Academic text (1993) -
By the mid-1990s, combinations of antiretroviral therapy, including protease inhibitors, were shown to significantly delay the onset of AIDS.
Blog text (29) -
This cutting or processing is initiated by the viral protease, which mutates rapidly, generating resistant variants for which the protease inhibitors have lost their effectiveness.
Blog text (27) -
A recent example of a second-generation drug that has narrowly avoided me-too labeling is the protease inhibitor, darunavir.
Blog text (19) -
The doctors prescribed a protease inhibitor to help manage his HIV infection.
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Many new antiviral treatments include a protease inhibitor as a key component of their effectiveness.
Synonyms
1
6.3
A drug that stops HIV from making more virus
A substance that stops enzymes in the body that break down proteins
Surface Forms
Morphology
The phrase is a direct noun–noun compound whose meaning ('a substance that inhibits protease enzymes') follows straightforward composition from 'protease' (an enzyme that breaks proteins) + 'inhibitor' (a substance that inhibits). Although it's a technical biomedical term, the semantic relation is transparent and predictable for a learner who knows both constituents and standard compounding patterns.
Etymology
The term protease inhibitor gives a clear picture: a protease works like tiny scissors that cut proteins, and an inhibitor is something that stops those scissors. So a protease inhibitor is a drug that 'blocks' the cutter and helps stop viruses like HIV from making new copies.