Skip to main content
Glite Dictionary
🕵️ Private detective 🧑‍🔬 Lead researcher 💊 HIV medicine
PI

PI

1 6.3
A drug that stops HIV from making more virus
  • noun
  • /piː/
  • Specialized
translation icon : inhibidor de proteasa
  • In combination therapy, a PI is often used to inhibit the replication of the virus.

Examples

  • Recent studies show that a PI can effectively lower viral loads in patients with HIV.

  • A1-PI and A2-M are the two important proteinase inhibitors present in plasma.

    Academic text (2007)

  • Table 1 shows, in patients with COPD, emphysema, bronchiectasis, and bronchial asthma, a1-PI and a2-M concentration are increased as compared with control.

    Academic text (2007)

  • A 1-PI is the chief proteinase inhibitor present in the highest amount inhibiting the serine proteinases elastase and trypsin.

    Academic text (2007)

  • Similar to our study, Denchev and colleagues (1977) estimated the a1-PI in patients with bronchial asthma with different forms and severity of the disease. a1-PI was found to be elevated in all patient groups.

    Academic text (2007)

  • The doctor prescribed a PI to help manage the patient's HIV infection.

Synonyms

protease inhibitor
vsPI
  • Specialized
5 5.3

A medicine that stops enzymes from breaking proteins and treats HIV

is the short written form used instead of the full term in clinical use

Compounds

pi-meson
  • Specialized
9.9

A small particle that helps hold the center of an atom together

pom pi pi
  • Baby Talk
9.9

A short, simple beat that keeps the rhythm in songs

Surface Forms

PI singular
PIs plural

Etymology

PI in medicine stands for protease inhibitor, where protease is a protein that 'cuts' other proteins and inhibitor means 'blocker' or 'stopper'. So a medical PI is a drug that 'blocks the protein cutter' and helps stop the virus from making more copies.