oligonucleotide
1
9.9
- noun
- /ˌoʊlɪɡoʊˈnjuːklɪəˌtaɪd/
- Specialized
:
oligonucleótido
- The oligonucleotide was designed to target a specific gene for the experiment.
- antisense oligonucleotides
- capture oligonucleotides
- oligonucleotide microarrays
And finally, an oligonucleotide is a run of DNA nucleotides, a run of DNA.
- And finally, an oligonucleotide is a run of DNA nucleotides, a run of DNA.
Examples
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Recently, the availability of increased probe densities has led to microarrays designed so that the individual oligonucleotide elements progressively tile the chromosomal sequences.
Academic text (2010) -
And finally, an oligonucleotide is a run of DNA nucleotides, a run of DNA.
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Any new technology is viewed with suspicion in the beginning; look at oligonucleotide therapeutics.
Blog text (21) -
Total genomic DNA from two individuals is sheared, fluorescently labeled, and hybridized to an array of synthesized oligonucleotides.
Academic text (2010) -
For example, graphene binds to single-stranded DNA effectively but not to double-stranded DNA and can protect oligonucleotides from enzymatic cleavage.
Academic text (2018) -
In these examples, microarrays were fabricated by Affymetrix using light-directed oligonucleotide synthesis to deposit sets of probes that are complementary to sequenced regions of the genome.
Academic text (2010) -
In genetic research, scientists often utilize oligonucleotides to analyze specific DNA sequences.
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For therapeutic applications, researchers have developed new oligonucleotides that can effectively bind to RNA.
Synonyms
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9.9
A short piece of DNA or RNA used in genetic research and testing
How Long
Surface Forms
Morphology
oligonucleotide = nucleotide (semi-transparent) = oligo + nucleotide + oligo
The composition 'oligo-' (few) + 'nucleotide' is formally predictable, but 'oligo-' is a technical combining form not familiar to many general learners.
Etymology
Oligonucleotide has two clear parts: oligo- meaning 'few' and nucleotide meaning 'small unit of DNA'. So it simply means a short chain of DNA building blocks, which is why scientists use the word for short pieces of genetic material in tests and research.