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deletion

deletion

3 6.7
A missing piece of DNA in a gene that changes how it works
  • noun
  • /dɪˈliːʃən/
  • Specialized
translation icon : deleción
  • Prior to data analysis, all data were screened, and a listwise deletion method was employed to eliminate missing data.
  • insertion-deletion
  • nucleotide deletion
  • listwise deletion

Essentially, they found that combinations of three nucleotide additions or three deletions were OK, suggesting a triplet code.

Examples

  • Unlike the original deletion strain, the transgenic animals reach adulthood but are very short-lived.

    Academic text (2017)
  • Omicron and Alpha test for these two, and this is because they have this genetic change called deletion in the spike S gene.

  • What appears to be a nucleotide deletion would still destroy any chance of getting results.

    Blog text (3)
  • Essentially, they found that combinations of three nucleotide additions or three deletions were OK, suggesting a triplet code.

  • In humans it is not functional and there have been three different mutations between humans and chimpanzees, an insertion, A deletion and a point mutation.

  • To directly test the effect of premature stop-encoding mutations in this gene, we generated a series of deletion alleles via CRISPR/Cas9 editing.

    Academic text (2017)
  • One infant had a genomic homozygous deletion, while two siblings had a heterozygous mutation in the fas gene.

    Academic text (2000)
  • Among the 15 DSPR founder strains, the 22-bp deletion allele at Ugt86Dd is fairly common (4/15 or 27%).

    Academic text (2017)
  • Scientists found that a small deletion in the gene caused a significant change in the organism's traits.

  • The deletion of several nucleotides on chromosome 22 can lead to serious health issues.

Synonyms

elimination
vsdeletion
77 3.5

The act of removing something you do not need

is a specific genetic loss of nucleotides causing a chromosome change

Antonyms

293 1.4

The act of putting one thing with another

15 4.2

The act of putting something into another thing

Compounds

self-deletion feature
  • Specialized
7.2

A program option that automatically removes messages or files after a set time

7.5

A feature that automatically removes files or messages after a set time

How Disruptive

frameshift
  • Specialized
9.6
to translocate
  • Specialized
9.9
deletion
  • Specialized
3 6.7
point mutation
  • Specialized
1 6.0
nonsynonymous
  • Specialized
9.3
missense
  • Specialized
9.8

Surface Forms

deletion singular
deletions plural

Morphology

deletion = delete (semi-transparent) = delete + ion

Formally derived from 'delete' (removal), but the genetic sense is a technical extension referring to loss of genetic material.

Etymology

The word deletion comes from the verb delete, from the old Latin delere meaning 'to wipe out' and the part de- meaning 'away'. So in genetics, a deletion is when a small piece of DNA has been taken 'away' or lost, which can change how a gene works.