frameshift
- noun
- /ˈfreɪmˌʃɪft/
- Specialized
:
mutación por desplazamiento de marco
- Even the ideas that the code was fully synchronized and fully sequential eventually came to be modified through the discovery of frameshift mutations and non-coding regions of the genome.
- frameshift deletion
Examples
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So that would be called a frameshift mutation that introduces a nonsense mutation and puts a stop codon into your messenger RNA.
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We also determined whether differentially expressed genes in each treatment group contained polymorphisms, including nonsynonymous single nucleotide polymorphisms (SNP), codon deletion, frameshift, etc.
Academic text (2016) -
The discovery of frameshift mutations has destroyed any residual belief in a natural synchronization of the genetic code.
Academic text (1996) -
The computer immediately reported three differences between what Mary had entered and what Reuben had, noting—it was an intelligent little program—a frameshift caused by Mary accidentally leaving off a U at one point; the other two errors were typos by Reuben.
Fiction book (2002) -
The scientist explained that a frameshift occurs when DNA bases are added or deleted, changing how the gene is read.
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Research on genetic diseases often involves studying frameshift mutations that can lead to improper protein formation.
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A frameshift can significantly affect an organism's traits by altering the way genes are expressed.
Synonyms
13
4.2
A permanent change in a gene's DNA that can alter traits
2
4.2
A permanent change in a gene that parents can pass to children
How Severe
- Specialized
- Specialized
- Specialized
2
4.2
- Specialized
Surface Forms
Morphology
Etymology
Frameshift comes from the two words frame ('a fixed starting point') and shift ('a move'). In genetics a frameshift is a change in the DNA that moves the reading frame, like changing where you start reading a line of text in small groups so every following part becomes different.