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Glite Dictionary
dabigatran

dabigatran

1 6.6
A medicine that prevents blood clots and lowers the risk of stroke
  • noun
  • /ˌdæbɪˈɡætrən/
  • Specialized
translation icon : dabigatrán
  • The doctor prescribed dabigatran to help reduce the risk of stroke in her patient with atrial fibrillation.
  • dabigatran over warfarin
  • Dabigatran 150 mg
  • Dabigatran 150 mg twice

Examples

  • Pradaxa, generic name Dabigatran, is an oral anticoagulant drug manufactured by the German pharmaceutical Boehringer Ingelheim.

    Blog text (6)

  • The Randomised Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial evaluated the efficacy and safety of dabigatran relative to warfarin in AF.

    Academic text (2010)

  • However, the greatest attraction will be that patients taking dabigatran do not take time to achieve therapeutic levels and also do not need monitoring.

    Academic text (2010)

  • Therefore, fluctuating kidney function may explain the increased bleeding with dabigatran in clinical practice.

    Academic text (2015)

  • So why aren't all our AF patients taking dabigatran?

    Academic text (2012)

  • Due to these pharmacologic properties, dabigatran and rivaroxaban may require more individualized dosing.

    Academic text (2017)

  • There was a significantly higher rate of major gastrointestinal bleeding with dabigatran at the 150-mg dose than with warfarin.

    Blog text (19)

  • The RE-LY Trial showed that dabigatran was effective (at high dose) for preventing stroke in paroxysmal or permanent AF.

    Academic text (2011)

  • Dabigatran acts on the coagulation cascade by directly inhibiting the action of thrombin.

    Academic text (2014)

  • In 285,947 patients with AF treated with NOACs, dabigatran was used most often (84.4%), followed by rivaroxaban (7.5%), edoxaban (4.9%), and apixaban (3.2%).

    Academic text (2017)

Synonyms

anticoagulant
vsdabigatran
  • Specialized
8 5.6

A medicine that slows or stops blood from forming clots

is a drug used particularly to prevent clots and reduce stroke risk
anticoagulant medication
vsdabigatran
  • Specialized
4.2

A medicine that stops or slows blood from forming clots

is used especially to reduce stroke risk in people with certain heart conditions
decoagulant
vsdabigatran
  • Specialized
8.7

A substance that stops or slows blood from forming clots

is prescribed to lower stroke risk especially in people with heart conditions

Surface Forms

dabigatran singular
dabigatrans plural

Etymology

Dabigatran is a modern, invented drug name; it was made for a medicine that blocks a part of the blood called thrombin that makes it 'clot'. So, dabigatran is used as a 'blood thinner' to prevent clots and reduce the risk of stroke.