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cobalamin

cobalamin

1 5.9
A B vitamin needed to make red blood cells and keep the nervous system healthy
  • noun
  • /ˌkoʊbəˈlæmɪn/
  • Specialized
translation icon : cobalamina
  • In fruit bats with cobalamin deficiency, there is no abnormality in S-adenosylmethionine or S-adenosylhomocysteine concentrations.
  • cobalamin (vitamin B12)

Examples

  • This biochemical pathway is the only known link between cobalamin and methylfolate metabolism.

    Academic text (1991)
  • Don't forget the "evolution" of the modern cobalamin plant was required, too.

    Blog text (28)
  • The addition of 75 g/kg methyl-cobalamin injected twice weekly for one month further normalised GSH:GSSG.

    Blog text (19)
  • She had hypomethioninaemia and homocystinuria with normal plasma and red-cell total cobalamin and folate concentrations.

    Academic text (1991)
  • There are two enzymes that have cobalamin as a cofactor, but deficiency of only one, methionine synthase, causes the characteristic neurological disease.

    Academic text (1991)
  • Recently, a double-blinded randomised controlled trial was published in which participants were administered either methyl-cobalamin or placebo for 6 weeks, and then their treatment was switched without washout for a further 6 weeks.

    Blog text (19)
  • Long-term deficiency of the vitamins cobalamin or folate can cause demyelination of the spinal cord and brain; the appearance of which is called subacute combined degeneration.

    Academic text (1991)
  • When consumed with folate (see next page), cobalamin has been shown to reduce the risk of cancer and heart disease.

  • People absorb less cobalamin from foods that contain the vitamin—dairy products and fish—as they grow older.

  • Long-term deficiency of the vitamins cobalamin or folate can cause demyelination of the spinal cord and brain; the appearance of which is called subacute combined degeneration.

Synonyms

vitamin B12
vscobalamin
  • Specialized
3 3.4

A vitamin that helps make red blood cells and keeps the nervous system healthy

is the scientific name for the same vitamin
antipernicious anemia factor
vscobalamin
  • Archaic
7.4

A vitamin called B12 that treats a serious type of anemia

is the modern scientific name rather than the old treatment name

Surface Forms

cobalamin singular
cobalamins plural

Morphology

cobalamin = cobalt + amine (opaque) = cobal + amin

The parts ('cobalt' and 'amine') are recognizable chemical elements/functional groups, but the specific identity 'vitamin B12' and its biological role are specialized and not directly inferable by general learners.

Etymology

Cobalamin comes from the metal cobalt and the chemical ending -amine, because this vitamin contains a cobalt atom at its centre. It is the same as vitamin B12 and is needed to make red blood cells and keep the nervous system healthy.