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bivalent

bivalent

8.9
An atom, ion, or molecule that can form two bonds
  • adjective
  • /ˌbaɪˈveɪlənt/
  • Specialized
translation icon : divalente
  • In molecular biology, a bivalent antibody can attach to two different antigens simultaneously.

Examples

  • Among the successful strategies are bivalent imidazolium salts, which have been shown to efficiently inhibit glycosyltransferase catalytic activity 197,198.

    Academic text (2016)
  • Monovalent OPV1 and bivalent OPV were used to control circulating WPV1.

    Academic text (2013)
  • Introduction of bivalent oral polio vaccine types 1 and 3 resulted in a dramatic decline in wild poliovirus cases to 42 in 2010 and only 1 case reported in January 2011 (2-5).

    Academic text (2012)
  • Reliance on monovalent OPV1, monovalent OPV3, and bivalent OPV in supplemental vaccination activities has contributed to the emergence of VDPV2.

    Academic text (2013)
  • Since December 2011, no cases of infection with WPV have been detected in DRC. Monovalent OPV types 1 and 3 and bivalent OPV effectively induce immunity because of a lack of interference by the type 2 component.

    Academic text (2013)
  • The bivalent nature of these ligands allows them to bind effectively to two separate sites on the target molecule.

  • Researchers often utilize bivalent compounds to enhance the efficacy of therapeutic agents in drug development.

Synonyms

divalent
vsbivalent
  • Specialized
8.9

Able to combine with two other atoms or ions

includes molecules as well and so applies to individual molecules

How Broad

polyvalent
  • Specialized
1 8.0
trivalent
  • Specialized
7.9
bivalent
  • Specialized
8.9
univalent
  • Specialized
9.6

Surface Forms

bivalent positive

Morphology

bivalent = valent (transparent) = bi + valent

Direct prefixation: 'bi-' (two) + 'valent' (having valence) straightforwardly yields 'having valence two', which is the standard chemical meaning.

Etymology

Bivalent comes from bi- 'two' and valent 'strength' or 'ability', and since 'valence' means how many bonds an atom can make, bivalent means 'able to form two bonds' and can also describe a vaccine that targets two strains.