bivalent
- adjective
- /ˌbaɪˈveɪlənt/
- Specialized
- In molecular biology, a bivalent antibody can attach to two different antigens simultaneously.
Examples
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Among the successful strategies are bivalent imidazolium salts, which have been shown to efficiently inhibit glycosyltransferase catalytic activity 197,198.
Academic text (2016) -
Monovalent OPV1 and bivalent OPV were used to control circulating WPV1.
Academic text (2013) -
Introduction of bivalent oral polio vaccine types 1 and 3 resulted in a dramatic decline in wild poliovirus cases to 42 in 2010 and only 1 case reported in January 2011 (2-5).
Academic text (2012) -
Reliance on monovalent OPV1, monovalent OPV3, and bivalent OPV in supplemental vaccination activities has contributed to the emergence of VDPV2.
Academic text (2013) -
Since December 2011, no cases of infection with WPV have been detected in DRC. Monovalent OPV types 1 and 3 and bivalent OPV effectively induce immunity because of a lack of interference by the type 2 component.
Academic text (2013) -
The bivalent nature of these ligands allows them to bind effectively to two separate sites on the target molecule.
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Researchers often utilize bivalent compounds to enhance the efficacy of therapeutic agents in drug development.
Synonyms
Able to combine with two other atoms or ions
How Broad
- Specialized
- Specialized
- Specialized
- Specialized
Surface Forms
Morphology
bivalent = valent (transparent) = bi + valent
Direct prefixation: 'bi-' (two) + 'valent' (having valence) straightforwardly yields 'having valence two', which is the standard chemical meaning.
Etymology
Bivalent comes from bi- 'two' and valent 'strength' or 'ability', and since 'valence' means how many bonds an atom can make, bivalent means 'able to form two bonds' and can also describe a vaccine that targets two strains.