single nucleotide polymorphism
- noun
- /ˈsɪŋɡəl ˈnjuːklɪəˌtaɪd ˌpɒlɪˈmɔːrfɪzm/
- Specialized
:
polimorfismo de un solo nucleótido
- Boldface highlights the different amino acid at each single nucleotide polymorphism between the two genotypes.
- single nucleotide polymorphism (SNP)
- single nucleotide polymorphisms (SNPs)
- single nucleotide polymorphism analysis
Examples
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These individual letter changes are known as single nucleotide polymorphisms or snips.
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In genetic research, a single nucleotide polymorphism can indicate susceptibility to certain diseases.
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And in this you have data on single nucleotide polymorphisms, a lot of them.
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L: Study of single nucleotide polymorphisms and other genetic variants.
Academic text (2009) -
The researchers analyzed 32 BMI-associated single nucleotide polymorphisms, or SNPs, previously linked to BMI.
Academic text (2015) -
For example, Dembeck et al. (2015) identified single nucleotide polymorphisms that contribute to quantitative differences in the suite of CHCs within D. melanogaster.
Academic text (2017) -
More robust methods for defining lineages, such as single nucleotide polymorphism analysis or whole-genome sequencing, may have allowed for more refined assignment of strain families in this study.
Academic text (2014) -
We satisfactorily genotyped 567,589 autosomal single nucleotide polymorphisms (SNPs) (mean call rate, 99.7%).
Academic text (2015) -
Overall, we analyzed 162 risk indicators in this study: 69 previously studied risk factors for mortality and 93 single nucleotide polymorphisms (SNPs).
Academic text (2012) -
Concatenated nucleotide sequences, including single nucleotide polymorphisms (SNPs), were then used for the construction of a neighbor-joining phylogenetic tree using MEGA software (24).
Academic text (2014)
Synonyms
10
8.6
A small change in DNA where one letter is different between people
Surface Forms
Morphology
single + nucleotide + polymorphism
The phrase is directly compositional: 'single' (one) + 'nucleotide' (a unit of nucleic acids) + 'polymorphism' (occurrence of multiple forms) yields a polymorphism affecting one nucleotide. Although technical, the meaning follows predictable morphological logic and similar constructions exist cross-linguistically, so a learner who knows the constituents can infer the intended sense.
Etymology
Single nucleotide polymorphism is often explained with a simple picture: think of DNA as a long sentence and a nucleotide as a single letter, so a single letter change makes a different 'form', which is what polymorphism means. So, the term refers to 'a one-letter change in DNA' that makes a small genetic difference between people.