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sickle cell

sickle cell

10 4.3
A red blood cell with a crescent shape that can block small blood vessels
  • noun
  • /ˈsɪkəl sɛl/
  • Specialized
translation icon : célula falciforme
  • Patients with sickle cell anemia and its variants were considered for inclusion.
  • sickle cell anemia
  • sickle cell disease
  • sickle cell trait

Examples

  • Catherine has sickle-cell anemia.

  • Some populations in Africa have high frequencies of the sickle cell gene.

    Academic text (1992)
  • The sickle cells must be blocking the blood flow again.

  • There's a disease of the blood called sickle-cell anemia.

  • He's got sickle cell anemia.

  • Inherited hemoglobin defects include sickle cell anemia and thalassemia.

    Academic text (2003)
  • Several genetically based diseases can now be identified, such as Down syndrome, Tay-Sachs disease, sickle cell anemia, cystic fibrosis, and Huntington's disease.

    Academic text (2007)
  • Some of the most known and publicized inheritable conditions are Tay-Sachs disease, muscular dystrophy, sickle cell disease, and cystic fibrosis.

    Academic text (2005)
  • A blood test can confirm the presence of sickle cell disease in patients.

  • One child out of four will inherit sickle cell disease if both parents carry the trait.

Surface Forms

sickle cell singular
sickle cells plural

Morphology

sickle + cell

The phrase is compositionally transparent: 'sickle' denotes a curved, crescent-like shape and 'cell' is a microscopic unit, so a B1 learner who knows both words can infer a cell shaped like a sickle. Although used in a medical context, the shape-based naming is straightforward and cross-linguistically common, so the meaning is predictable from the constituents.

Etymology

Sickle cell comes from the curved farming tool called a sickle, because some red cells bend into the same curved shape. That's why doctors call these bent blood cells 'sickle cells' and why the disease uses the same name.