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phase II clinical trial

phase II clinical trial

4.2
A medical test with more people to see if a treatment works and check for side effects
  • noun
  • /feɪz tuː ˈklɪnɪkəl traɪəl/
  • Specialized
translation icon : ensayo clínico de fase II
  • A pyrimidine carboxamide similar in structure to raltegravir was recently propelled into Phase II clinical trials by a separate group.

Examples

  • After analyzing the data, the researchers concluded that the Phase II clinical trial successfully evaluated the treatment's effectiveness.

  • The results of the study, a Phase II clinical trial, indicated that in about half the participants, treatment was effective in reducing their stuttering to acceptable levels.

    Academic text (2014)
  • The design was a Phase II clinical trial with blinded outcome assessments pretreatment, on entry to the maintenance stage of treatment, and 6 and 12 months after entry to maintenance.

    Academic text (2014)
  • Purpose: This Phase II clinical trial examined stuttering adolescents' responsiveness to the Webcam-delivered Camperdown Program.

    Academic text (2014)
  • A Phase II clinical trial of a new diabetes medication that requires the subjects in the control group to receive a placebo would be exploitative, because there are inexpensive, effective treatments available for diabetes, and not taking medication for diabetes has serious health consequences (Miller & Brody 2002).

    Academic text (2008)
  • The Phase II clinical trial showed promising results for the new cancer treatment among participants.

  • In a recent Phase II clinical trial, patients reported fewer side effects compared to earlier stages of treatment.

Synonyms

phase II
vsphase II clinical trial
  • Specialized
2 4.7

A clinical trial stage testing a new treatment in many people to see if it works and check side effects

is the full formal term rather than the shorter stage label

How Advanced

phase IV clinical trial
  • Specialized
5.1
phase III clinical trial
  • Specialized
1 5.0
phase II clinical trial
  • Specialized
4.2
phase I clinical trial
  • Specialized
1 4.3
preclinical test
  • Specialized
5.6

Surface Forms

Morphology

phase + II + clinical + trial

Each constituent directly contributes to the overall meaning: 'phase' = stage, 'II' = two, 'clinical' = medical/patient-related, and 'trial' = testing. A B1 learner who knows these words can reasonably infer this refers to the second stage of medical testing to evaluate effectiveness and monitor side effects; numbering of phases is a common, cross-linguistically transparent convention.

Etymology

Phase II clinical trial comes from the idea of testing a new treatment in numbered steps: phase means a step and II is the second step. After a small first test, this second step gives the treatment to more people to see if it really works and to watch for 'side effects', so the phrase means a larger test of 'effectiveness' and safety.