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Glite Dictionary
phase III

phase III

2 3.7
The third stage of testing a new medicine in many people before approval
  • noun
  • /feɪz θriː/
  • Specialized
translation icon : fase III
  • Therefore, efforts to monitor for toxicities after completing pivotal phase III RCTs are essential.
  • phase III trial
  • phase III study

Examples

  • Parameters for evaluating vaccine efficacy must be defined precisely to facilitate measurement and evaluation in phase III trials.

    Academic text (1999)

  • The overall effects of the Phase III trial failed to show that the drug was effective for treating IPF. Id.

    Academic text (2016)

  • The company also announced in August a second Phase III trial for U.S. approval.

    Blog text (6)

  • The side effects described in the phase III trial were most severe in the first two treatment cycles.

    Academic text (2007)

  • Later in Phase III, the former Interim Dean became a member of the team.

    Academic text (1990)

  • Finally, in the USA, a phase III trial with brain-derived neurotrophic factor is being initiated.

    Academic text (2000)

  • In 2013 dollars, these costs averaged $58.6 million for Phase II and $255.4 million for Phase III trials.

    Academic text (2016)

  • The clinical efficacy of Gla-300 in patients with T1DM was shown in two Phase III studies: EDITION 4 and EDITION JP 1.36, 37.

    Academic text (2017)

  • The study was a Phase III, 26-week, randomized controlled, open-label, multicenter, 3-arm, parallel-group trial.

    Academic text (2017)

  • We have just completed a Phase III trial in Europe and South Africa, which aimed to confirm the treatment's effectiveness.

Synonyms

phase III clinical trial
vsphase III
  • Specialized
1 5.0

A large study that tests a medicine's effects and side effects before approval

is the same stage but aimed at approval by the US FDA

How Advanced

phase IV
  • Specialized
6.0
phase III
  • Specialized
2 3.7
phase II
  • Specialized
2 4.7
phase I
  • Specialized
2 4.3
preclinical test
  • Specialized
5.6

Surface Forms

phase III singular
phase IIIs plural

Morphology

phase + III

The meaning is directly compositional: 'phase' = a distinct stage and 'III' = three, so a learner who knows both constituents can infer it means the third stage. Although the specific domain details of clinical trials (what happens in Phase III) require background knowledge, the ordinal/stage relation is transparent and cross-linguistically predictable.

Etymology

Phase III comes from thinking of a process in steps called phases, with III meaning the third step. One clear image is a three-step test where the third step is the large 'final' check with many patients, so Phase III means the big trial that checks a treatment works and is safe before approval.