Skip to main content
phase III clinical trial

phase III clinical trial

1 5.0
A large study that tests a medicine's effects and side effects before approval
  • noun
  • /feɪz θriː ˈklɪnɪkəl traɪəl/
  • Specialized
translation icon : ensayo clínico de fase III
  • Careful phase III clinical trials are now needed to confirm the efficacy in humans.
  • Phase III clinical trial of the drug

Examples

  • I am one of the lucky 150 men who entered the ipilumimab prostate cancer phase III clinical trial in the USA (another 450 men are enrolled worldwide).

    Blog text (34)
  • Even phase III clinical trials, which usually involve several hundred to 3,000 volunteer subjects, are unlikely to reveal every adverse effect.

  • Similar clinical and imaging benefits have been observed in phase III clinical trials of interferon beta in patients with secondary progressive multiple sclerosis.

    Academic text (2002)
  • 23 Across Phase III clinical trials, a fixed dose of abatacept, determined according to weight range, was administered over a 30-minute infusion at Weeks 0, 2, and 4, and then every 4 weeks thereafter.

    Academic text (2007)
  • Findings from a phase III clinical trial of about 300 women may introduce PARP inhibitors as a new type of treatment for breast cancer.

Synonyms

phase III
vsphase III clinical trial
  • Specialized
2 3.7

The third stage of testing a new medicine in many people before approval

has the same meaning but uses the longer full phrase form

How Advanced

phase IV clinical trial
  • Specialized
5.1
phase III clinical trial
  • Specialized
1 5.0
phase I clinical trial
  • Specialized
1 4.3
phase II clinical trial
  • Specialized
4.2
preclinical test
  • Specialized
5.6

Surface Forms

Morphology

phase + III + clinical + trial

The phrase is compositionally built from its parts: 'phase' (stage) + 'III' (three) + 'clinical trial' (patient-based testing), so a B1 learner who knows the constituent words can infer it refers to the third stage of medical testing. Although full regulatory or scale-specific details are technical, the core meaning is directly derivable from the components and follows common cross-linguistic staging conventions.

Etymology

Phase III clinical trial names the third big test of a new treatment in people. Think of phase as a stage and III as the third stage, and a clinical trial as a test in patients, so a phase III trial is the large final test where many patients try the treatment to make sure it works and to watch for side effects before health officials approve it.