neurofibrillary
1
9.9
- adjective
- /ˌnjʊəroʊˈfaɪbrəˌlɛri/
- Specialized
- In Alzheimer's patients, the presence of neurofibrillary tangles is a significant indicator of disease progression.
- neurofibrillary tangles
- neurofibrillary plaques
Examples
-
When Alzheimer did an autopsy of her brain, he found unexpected beta amyloid plaques and neurofibrillary tangles, which made him suspect that he had discovered some new pathology.
Academic text (2014) -
When tau is defective, most often due to changes introduced during protein synthesis, it can accumulate in neurofibrillary tangles, one of the primary markers of Alzheimer's.
Blog text (20) -
Lawyers for Mr. K had introduced studies showing that monkeys exposed to radio waves developed neurofibrillary tangles, a classic sign of Alzheimer's disease.
Fiction book (1998) -
As well as identifying plaques, Alzheimer identified neurofibrillary tangles under light microscopy.
Academic text (1992) -
Which is as the amyloid beta plaques and the neurofibrillary tangles are wreaking havoc in the neurons.
-
Further reports suggest correlations between cognitive dysfunction and dystrophic neurites and neurofibrillary tangles (NFT).
Academic text (1995) -
They would work to break down amyloids, dismantle neurofibrillary tangles, and repair neurons sheared apart by the force of an opponent's fists.
Fiction book (2001) -
Studies indicate that neurofibrillary tangles disrupt normal brain function and are linked to cognitive decline.
-
Research has shown that the accumulation of neurofibrillary tangles correlates with severe memory loss in affected individuals.
Synonyms
1
7.7
Having many tiny threads in body tissue
1
9.0
Having thin fibers in body tissue
Surface Forms
Morphology
neurofibrillary = neurofibril (semi-transparent) = neuro + fibril + ary
The adjective is formed by adding '-ary' to the technical noun 'neurofibril', but the term remains specialized biological vocabulary.
Etymology
The word neurofibrillary breaks into neuro- meaning 'nerve' and fibr- like in fiber, meaning 'thread' or 'fiber'. So it describes the small thread-like parts found in nerve cells.