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monosomy

monosomy

9.9
A condition when one of a pair of chromosomes is missing in body cells
  • noun
  • /ˈmɒnəˌsoʊmi/
  • Specialized
translation icon : monosomía
  • A common example of monosomy is Turner syndrome, where one X chromosome is missing in female individuals.

Examples

  • Researchers have identified several health issues associated with monosomy, particularly in developmental biology.

  • Of course, with the basics of the 46 chromosomes of the human genome, it is easy enough to recognize an addition or deletion of one or another gene or chromosome abnormality, as with trisomy or monosomy conditions.

    Academic text (2005)
  • In genetics, the term monosomy refers to the loss of one chromosome from a pair within a diploid organism.

Synonyms

chromosomal abnormality
vsmonosomy
  • Specialized
1 6.1

A change in the number or shape of chromosomes that often causes health problems

is limited to the case of one missing chromosome rather than all changes
chromosomal anomaly
vsmonosomy
  • Specialized
1 6.7

A change in the number or shape of chromosomes that often causes health problems

is a single missing chromosome case rather than any abnormal change
aneuploidy
vsmonosomy
  • Specialized
1 9.9

An abnormal number of chromosomes in a cell that is not the usual amount

is the specific case where one chromosome of a pair is absent
chromosomal aberration
vsmonosomy
  • Specialized
1 8.9

A change in the usual number or shape of chromosomes that often causes physical and mental problems

is specifically the absence of one chromosome from a pair
chromosomal disorder
vsmonosomy
  • Specialized
1 5.3

A health condition caused by a change in chromosomes that can affect the body or mind

is the specific genetic situation where one chromosome from a pair is missing
heteroploidy
vsmonosomy
  • Specialized
9.9

A condition in which an organism has a different number of chromosomes than normal for its species

is a single missing chromosome from a pair rather than any number change

Surface Forms

monosomy singular
monosomies plural

Morphology

monosomy = mono + som + y

Although the word contains the familiar prefix 'mono-' and a bound Greek root, the medical meaning of a chromosome missing from a pair is specialized and not predictable for an average learner.

Etymology

Monosomy comes from the Greek parts mono- meaning 'one' and soma meaning 'body', and you can think of mono- like in monologue ('one'). So monosomy literally suggests 'one body' and is used when one chromosome of a pair is missing from the usual set.