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lyase

lyase

1 9.7
A substance in cells that breaks parts off molecules without using water or oxygen
  • noun
  • /ˈlaɪeɪs/
  • Specialized
: liasa
  • The biochemical process relies on a specific lyase to convert fats into usable energy.

Examples

  • Researchers studied the lyase that helps in the breakdown of complex sugars into simpler forms.

  • Use ISO citrate lyase to generate glyoxylate.

  • Patients with typical manifestations of CAIS and 17-alpha-hydroxylase/17,20-lyase deficiency were excluded.

    Academic text (2018)
  • Galeterone is a novel CYP17 lyase inhibitor that is structurally very similar to Abiraterone 117.

    Academic text (2017)
  • An exploration of the functional significance of several SNPs in the gene for cystathione lyase associated with autistic disorder may shed light on this putative relationship.

    Blog text (19)
  • In other environments, the limiting nutrient is not that obvious; for example, the acquisition of N-acetylneuraminate lyase probably enables T. vaginalis to scavenge sialic acids from its host for nutrition 117.

    Academic text (2018)
  • The enzyme lyase catalyzes the cleavage of bonds in substrates without the involvement of water.

Surface Forms

lyase singular
lyases plural

Morphology

lyase = lysis (semi-transparent) = ly + ase

The suffix '-ase' clearly signals an enzyme (transparent), but the root 'ly-'/ 'lys-' is a technical combining form meaning 'break/loosen' that is not obvious to an average learner.

Etymology

Lyase comes from an old Greek root lysis, meaning 'to loosen' or 'to break', plus the enzyme ending -ase. So a lyase is an enzyme that 'breaks' chemical bonds without using water or oxygen.