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lipopolysaccharide

lipopolysaccharide

1 9.9
A large chemical in the outer wall of some bacteria that makes the body react strongly
  • noun
  • /ˌlaɪpoʊˌpɑːliˈsækəraɪd/
  • Specialized
: lipopolisacárido
  • Researchers found that exposure to lipopolysaccharide triggers inflammation in human cells.

So things like endotoxin, lipopolysaccharide, just the cell wall of the bacteria.

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Examples

  • The morphology of stem cells was characterized by flat shapes and increased size after stimulation with lipopolysaccharide.

    Academic text (2018)
  • The injection of lipopolysaccharide stimulated a strong immune response in the laboratory mice.

  • So things like endotoxin, lipopolysaccharide, just the cell wall of the bacteria.

  • Lipoproteins bind this lipopolysaccharide to help, you know, prevent our bodies from having massive inflammation and, and, and base undergoing sepsis.

  • Administration of sST2 also reduced lipopolysaccharide (LPS)-induced inflammatory response and mortality 21.

    Blog text (17)
  • JMJD3 is known to mediate an inflammatory response in cells exposed to lipopolysaccharide (LPS), but the mechanism of this activity was not known.

    Blog text (6)
  • Common bacterial glycoconjugates include the capsular polysaccharide, glycosylated proteins, lipopolysaccharide (LPS), and peptidoglycan.

    Academic text (2018)
  • However, the ability of human astrocytes to respond directly to lipopolysaccharide (LPS) — a structural component of the outer envelope of all gram-negative bacteria — is still in debate 20, 21.

    Academic text (2018)
  • The study concluded that lipopolysaccharide plays a crucial role in the activation of the immune system.

Surface Forms

Morphology

lipopolysaccharide = polysaccharide (semi-transparent) = lipo + poly + saccharide

The term is built from standard scientific morphemes, but its specialized biochemical meaning is not directly guessable for an average learner.

Etymology

Lipopolysaccharide comes from parts you can read: lipo- means 'fat' and poly- + saccharide means 'many sugars'. It is a molecule made of fat with many sugars on the outside of some bacteria, which is why it can cause a strong reaction in the body's immune system.