infliximab
- noun
- /ɪnˈflɪksɪmæb/
- Specialized
- This is what happened to Joseph Phillips, an Illinois man who, five years after beginning a treatment protocol involving the drugs Remicade (infliximab injection) and Imuran (azathioprine), developed chronic myeloid leukemia, a severe form of blood cancer.
- infliximab and etanercept
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Watch on YouTubeIt stopped my infliximab from working so suddenly.
- It stopped my infliximab from working so suddenly.
Examples
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Etanercept is a recombinant soluble receptor TNF-R2-IgG1, whereas infliximab is a chimeric monoclonal antibody 105.
Academic text (2016) -
Treatment of RA with anti-TNF monoclonal antibodies such as infliximab and adalimumab has been found to induce and restore the functions of Tregs 134.
Blog text (11) -
It stopped my infliximab from working so suddenly.
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Also, omega-3 fish oil is recommended; just a thought, you have nothing to lose. I am now on my first infusion of infliximab because nothing else works.
Blog text (2) -
Importantly, blockade of TNF activity by infliximab directly or indirectly affects TNF mRNA expression during T. cruzi infection.
Academic text (2016) -
Although significantly reduced in infliximab-treated mice compared to saline-injected ones, TNF mRNA expression was not abolished in the heart tissue during T. cruzi infection.
Academic text (2016) -
While infliximab and etanercept both neutralize the soluble form of TNF, infliximab binds more powerfully to the membrane form of TNF than etanercept does.
Academic text (2016) -
While infliximab and etanercept both neutralize the soluble form of TNF, infliximab binds more powerfully to the membrane form of TNF than etanercept does.
Academic text (2016) -
The doctor prescribed infliximab to help manage her Crohn's disease effectively.
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Patients with rheumatoid arthritis often benefit from treatment with infliximab and methotrexate.
Synonyms
A brand-name medicine given by infusion to treat diseases of the immune system like Crohn's disease and rheumatoid arthritis
Surface Forms
Etymology
Infliximab is built like many antibody drug names: the ending -mab means 'monoclonal antibody', a lab-made antibody used as a medicine. A helpful way to remember inflix is to hear 'inflammation' + 'fix', so infliximab is an antibody medicine that helps 'fix' harmful inflammation in conditions like Crohn's disease and rheumatoid arthritis.