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infliximab

infliximab

1 9.6
A medicine that treats illnesses when the body's immune system attacks itself
  • noun
  • /ɪnˈflɪksɪmæb/
  • Specialized
: infliximab
  • This is what happened to Joseph Phillips, an Illinois man who, five years after beginning a treatment protocol involving the drugs Remicade (infliximab injection) and Imuran (azathioprine), developed chronic myeloid leukemia, a severe form of blood cancer.
  • infliximab and etanercept

It stopped my infliximab from working so suddenly.

Examples

  • Etanercept is a recombinant soluble receptor TNF-R2-IgG1, whereas infliximab is a chimeric monoclonal antibody 105.

    Academic text (2016)
  • Treatment of RA with anti-TNF monoclonal antibodies such as infliximab and adalimumab has been found to induce and restore the functions of Tregs 134.

    Blog text (11)
  • It stopped my infliximab from working so suddenly.

  • Also, omega-3 fish oil is recommended; just a thought, you have nothing to lose. I am now on my first infusion of infliximab because nothing else works.

    Blog text (2)
  • Importantly, blockade of TNF activity by infliximab directly or indirectly affects TNF mRNA expression during T. cruzi infection.

    Academic text (2016)
  • Although significantly reduced in infliximab-treated mice compared to saline-injected ones, TNF mRNA expression was not abolished in the heart tissue during T. cruzi infection.

    Academic text (2016)
  • While infliximab and etanercept both neutralize the soluble form of TNF, infliximab binds more powerfully to the membrane form of TNF than etanercept does.

    Academic text (2016)
  • While infliximab and etanercept both neutralize the soluble form of TNF, infliximab binds more powerfully to the membrane form of TNF than etanercept does.

    Academic text (2016)
  • The doctor prescribed infliximab to help manage her Crohn's disease effectively.

  • Patients with rheumatoid arthritis often benefit from treatment with infliximab and methotrexate.

Synonyms

Remicade
vsinfliximab
  • Specialized
1 8.2

A brand-name medicine given by infusion to treat diseases of the immune system like Crohn's disease and rheumatoid arthritis

is the active monoclonal antibody ingredient rather than a brand product

Surface Forms

infliximab singular
infliximabs plural

Etymology

Infliximab is built like many antibody drug names: the ending -mab means 'monoclonal antibody', a lab-made antibody used as a medicine. A helpful way to remember inflix is to hear 'inflammation' + 'fix', so infliximab is an antibody medicine that helps 'fix' harmful inflammation in conditions like Crohn's disease and rheumatoid arthritis.