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homeobox

homeobox

1 9.9
A short DNA section inside genes that controls how an embryo's body parts form
  • noun
  • /ˈhoʊməˌbɑks/
  • Specialized
translation icon : homeobox
  • In mice, homologues of the Drosophila homeotics are called Hox genes (for "homeobox containing").
  • homeobox gene

Examples

  • At that point, sharing the excitement of my colleagues, I wrote a column in November 1985 entitled "Geoffroy and the Homeobox," suggesting that the presence of homeoboxes in both insects and vertebrates might validate Geoffroy's vision of common design.

    Academic text (1992)
  • Now some of the evidence on that have come from gene expression data, homeobox gene expression in particular.

  • OK, can somebody tell me what the homeobox genes are often called Hox genes?

  • Processed pseudogenes such as POU class 5 homeobox 1B (POU5F1B) that are highly homologous to OCT4 were recently shown to be transcribed in cancer cells.

    Academic text (2016)
  • No one knew how the transcribed protein might function (with its 60 amino acids according to the genetic code of 3 base pairs per amino acid), but its presence within homeotic genes led to its designation as the "homeobox."

    Academic text (1992)
  • Researchers found that homeobox genes play a crucial role in determining the body plan during embryonic development.

  • The homeobox is a vital DNA sequence that regulates the expression of developmental genes in many species.

  • Scientists study homeobox genes to understand how organisms develop specific body structures and segments.

Compounds

homeobox gene
  • Specialized
8.1

A gene that has a homeobox part and controls how an embryo's body forms

Surface Forms

homeobox singular
homeoboxes plural

Morphology

homeobox = homeotic + box (opaque) = homeo + box + homeo

The combining form 'homeo-' is a specialised biological element (not 'home' meaning house) and 'box' has a technical 'sequence motif' sense, so the compound's meaning is not derivable by an average B1 learner.

Etymology

The word homeobox comes from the root homeo- meaning 'same' and box meaning 'a small container'. It names a short, similar 'box' of DNA found in many genes that helps decide how a developing animal's body is built, so the name shows why this tiny DNA part has the same role in many animals.