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Glite Dictionary
🧬 A genetic error 🧬 To change reading
to frameshift

to frameshift

9.9
To change how a gene is read by adding or removing DNA letters
  • verb
  • /ˈfreɪmʃɪft/
  • Specialized
translation icon : desplazar el marco
  • A single nucleotide insertion can frameshift the entire gene sequence, leading to a nonfunctional protein.

Examples

  • Scientists discovered that certain chemicals can frameshift DNA during replication.

  • If you frameshift the sequence, the resulting protein may be completely different from the original.

  • A single nucleotide can frameshift the entire genetic sequence.

  • Did the scientist frameshift the DNA sequence?

  • If you frameshift the DNA sequence by deleting a nucleotide, it could change the entire protein that is produced.

  • A specific mutation can frameshift the reading frame, causing significant changes in the resulting protein structure.

  • The researchers aim to frameshift the genetic code in order to study the effects on protein synthesis.

Synonyms

to edit
vsto frameshift
  • Specialized
3 5.8

To change a living thing's DNA to add or remove genes

causes a reading frame change by inserting or deleting nucleotides downstream

Surface Forms

frameshift infinitive
frameshifted past
frameshifted past participle
frameshifting present participle
frameshifts third person singular

Etymology

Frameshift as a verb comes from frame ('a fixed starting point') and shift ('a move'), so it means to move that start. In genetics to frameshift is to insert or remove a letter in the DNA so the place you begin reading moves, which makes everything after it read differently.