decarboxylase
1
9.9
- noun
- /ˌdiːkɑːrˈbɒksɪleɪs/
- Specialized
- The decarboxylase enzyme is essential for the conversion of amino acids into other important molecules in the body.
- acid decarboxylase
Examples
-
Dopa decarboxylase plays a crucial role in the synthesis of neurotransmitters by removing a carboxyl group from its substrate.
-
Conclusions: The numbering scheme serves as a tool for the reliable sequence alignment of ThDP-dependent decarboxylases and the unambiguous identification and communication of corresponding positions.
Blog text (27) -
Results: We developed and validated a standard numbering scheme for the family of ThDP-dependent decarboxylases.
Blog text (27) -
In addition, a putative decarboxylase with sequence homology to a coccolith-associated protein was significantly up-expressed.
Blog text (18) -
A profile hidden Markov model (HMM) was created using a set of representative sequences from the family of ThDP-dependent decarboxylases.
Blog text (27) -
Despite a high structural similarity between the members of the ThDP-dependent decarboxylases, their sequences are diverse and make a pairwise sequence comparison of protein family members difficult.
Blog text (27) -
Dopa decarboxylase 79 and the human imprinted GRB10 80 and IGF2 77, 81 genes.
Blog text (26) -
Alternative pathways that could utilize HCO3- were also suggested by the gene expression profiles (e.g., putative propionyl-CoA and methylmalonyl-CoA decarboxylases).
Blog text (18) -
Researchers are studying the activity of a specific decarboxylase to understand its function in metabolic pathways.
Surface Forms
Morphology
decarboxylase = carboxylase (semi-transparent) = de + carboxyl + ase
In scientific vocabulary, adding 'de-' to 'carboxylase' transparently signals removal or reversal of carboxylation.
Etymology
Decarboxylase is made of three parts: de- 'remove', carboxyl 'a group with carbon and oxygen', and -ase 'the ending used for enzyme names'. So it literally means an enzyme that removes a carboxyl group from a molecule.