autosomal dominant disorder
1
6.5
- noun
- /ˌɔːtəˈsoʊməl ˈdɑːmɪnənt dɪsˈɔːrdər/
- Specialized
:
trastorno autosómico dominante
- However, achondroplasia is an autosomal dominant disorder, and one would expect to see other children affected in the family.
Examples
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Isolated primary VUR is an autosomal dominant disorder with incomplete penetrance and variable expression: the genetic defect or defects are unknown.
Academic text (2000) -
Thus, the offspring of a woman with a single gene/autosomal dominant disorder who becomes pregnant by a man with the same single gene/autosomal dominant disorder will inherit the gene and express the disease.
Academic text (2005) -
It's a genetic autosomal dominant disorder that results in uncontrollable sneezing in response to numerous stimuli such as looking at bright lights.
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Huntington's disease is an autosomal dominant disorder with high penetrance characterized by progressive chorea and dementia.
Academic text (2004) -
Thus, the offspring of a woman with a single gene/autosomal dominant disorder who becomes pregnant by a man with the same single gene/autosomal dominant disorder will inherit the gene and express the disease.
Academic text (2005) -
Achondroplasia is an autosomal dominant disorder that affects bone growth and is visible at birth.
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Huntington's disease, an autosomal dominant disorder, leads to progressive loss of motor control and cognition.
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If one parent has an autosomal dominant disorder, there is a 50 percent chance their children will inherit it.
Synonyms
A genetic disease from a changed gene on a non-sex chromosome where one bad copy causes illness
Surface Forms
Morphology
autosomal + dominant + disorder
The phrase is transparently built from its parts: 'autosomal' (relating to non‑sex chromosomes) + 'dominant' (expressed when a single copy is present) + 'disorder' (a medical condition). A learner who knows these constituent meanings can infer it denotes a medical condition caused by a dominant gene on an autosome; although technical, the modifier+noun composition is regular and compositional.
Etymology
The term autosomal dominant disorder breaks into autosomal (a gene on a chromosome not related to being male or female) and dominant (a gene where one bad copy is enough to 'show' the condition). So, if a parent has this kind of gene, each child usually has about a 50% chance to inherit the disorder.