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TNF

TNF

4 7.9
A protein made by white blood cells that causes inflammation and helps the immune system
  • noun
  • Specialized
translation icon : TNF
  • Previous investigations also demonstrated that IFN-gamma and TNF-alpha could significantly enhance osteogenesis.
  • TNF antagonist
  • TNF levels
  • TNF production

So these include TNF alpha Illinois one.

Examples

  • Research has shown that high levels of TNF can contribute to inflammation in rheumatoid arthritis.

  • More importantly, humans with Chagas disease have increased levels of circulating TNF 41,58.

    Academic text (2016)
  • Thus, it is possible to reason that TNF plays a complex role during Chagas disease.

    Academic text (2016)
  • However, several lines of evidence demonstrated a possible crosstalk between TNF and these substances.

    Academic text (2016)
  • However, the question of whether the risk for cancer is increased with TNF inhibitors still requires clarification.

    Academic text (2015)
  • Cluster 4 mostly consisted of proteins that only changed levels significantly in the TNF and LPS groups.

    Academic text (2018)
  • Our results showed that CD106 expression level was significantly upregulated by TNF-alpha on the third day.

    Academic text (2018)
  • They saw that the TNF alpha was causing apoptosis or cell death of the endothelial cells.

  • We also observed that IL-1 beta, as well as TNF-alpha, enhanced chondrogenic differentiation capacity in vitro.

    Academic text (2018)
  • In patients with rheumatoid arthritis (RA), are some tumor-necrosis factor (TNF) inhibitors safer than others?

    Academic text (2015)

Synonyms

tumor necrosis factor
vsTNF
  • Specialized
5.3

Some white blood cells make a protein that causes inflammation and can kill cancer cells

has identical meaning but is the abbreviated form used in technical texts

Compounds

anti-TNF compound
  • Specialized
4.8

A medicine that blocks a protein that causes inflammation, used for diseases like rheumatoid arthritis

Surface Forms

TNF singular
TNFs plural

Morphology

TNF = T + N + F

TNF is an initialism (letters standing for 'tumor necrosis factor'); the letters do not transparently convey the meaning to learners.

Etymology

TNF is a short form made from three words: tumor 'lump' or 'growth', necrosis 'death' of tissue, and factor 'a thing that causes something'. Because this protein is made by white blood cells and can make cells die and cause strong inflammation, scientists named it TNF, which explains the name and what it does.