vimentin
- noun
- /vaɪˈmɛntɪn/
- Specialized
- The epithelial component exhibited a positive immunohistochemical reaction to cytokeratin and a negative reaction to vimentin, whereas the mesenchymal component showed a positive immunohistochemical reaction to vimentin and a negative reaction to cytokeratin.
- positive for vimentin
- vimentin but negative
- vimentin and cytokeratin
Examples
-
Immunohistochemical studies show a positive reaction with vimentin, but negative for desmin, S-100 protein, and cytokeratin.
Academic text (1996) -
Immunohistochemical studies showed positive staining of tumor cells for vimentin and focally for S-100 protein.
Academic text (2003) -
All the experimental groups showed strong positive expression for vimentin.
Academic text (2018) -
Immunohistochemistry was positive for CD99, vimentin, BCL2, and CD56.
Academic text (2015) -
They are immunoreactive for vimentin and not immunoreactive for HMB-45.
Academic text (2004) -
Immunoperoxidase stains were positive for vimentin but negative for cytokeratin, chromogranin, S-100 protein, synaptophysin, ULEX europeus, and LCA.
Academic text (1996) -
Immunohistochemistry has been used in the past to help differentiate this tumor from non-neural derived lesions, with vimentin and neuron-specific enolase being positive and cytokeratin being absent.
Academic text (1996) -
Immunohistochemistry can demonstrate antibodies to S-100, vimentin, smooth-cell actin, desmin, CD34, and neuron-specific enolase.
Academic text (2009) -
Researchers found that the presence of vimentin in the tissue samples indicated the tumors were of mesenchymal origin.
-
In their analysis, they observed that the cells expressed vimentin, which helped confirm the diagnosis of a specific tumor type.
Surface Forms
Morphology
vimentin = viment (opaque) = viment + in
The element 'viment' is a specialized combining form (not a standalone modern English word) and '-in' is a protein-suffix; the combination is scientific and not transparently interpretable by general learners.
Etymology
The word vimentin comes from the Latin vimen, meaning 'twig', plus the common protein ending -in, giving the idea of thin, supporting threads. That's why scientists use vimentin as a lab marker for mesenchymal cells and some types of tumors, because those cells show these thread-like supports.
