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vimentin

vimentin

1 9.9
A protein in many cells, especially connective tissue, that helps keep cell shape
  • noun
  • /vaɪˈmɛntɪn/
  • Specialized
: vimentina
  • Endothelial function and integrity can also be affected by cytoskeleton-interacting proteins that are involved in mechanosensing, such as filamin A, vimentin, and plectin, which were upregulated in the HF kidney.
  • vimentin and actin

Examples

  • Immunohistochemical analysis confirmed that vimentin is present in many fibroblastic cells.

  • The presence of vimentin in tissue samples indicates the strength of the connective structure.

  • S (BLACK & WHITE): Figure 3. A: Stain for vimentin (V9) shows strong positivity. Note that the tumor cells are arranged.

    Academic text (2001)
  • Immunohistochemical studies yielded positive vimentin staining of the fibroblastic spindle cells.

    Academic text (2003)
  • Leiomyosarcoma cells are frequently positive for vimentin, smooth muscle actin, and muscle-specific or pan-muscle actin.

    Academic text (2001)
  • The spindle cells exhibited no particular architecture in the spindle cells with desmin, smooth-muscle actin, and vimentin.

    Academic text (2004)
  • The tumor cells showed strong cytoplasmic immunoexpression of vimentin, pankeratin, S-100 protein, and smooth-muscle actin.

    Academic text (2009)
  • In tumor pathology, vimentin is used as a marker to identify mesenchymal tumors.

Surface Forms

vimentin singular
vimentins plural

Morphology

vimentin = viment (opaque) = viment + in

The element 'viment' is a specialized combining form (not a standalone modern English word) and '-in' is a protein-suffix; the combination is scientific and not transparently interpretable by general learners.

Etymology

The word vimentin comes from the Latin vimen, meaning 'twig', plus the common protein ending -in. So vimentin is like a tiny thread or twig inside cells that helps hold their shape and supports connective tissue.