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transversion

transversion

1 9.9
A change in DNA where one base is replaced by another
  • noun
  • /trænzˈvɜrʒən/
  • Specialized
translation icon : transversión
  • Although neighboring effects in general are still important, prominent influences such as the elevated CpG transversion rate previously identified using the TF form are an artifact.

Examples

  • Specifically, the NF model does not recognize a significant context-dependent influence on transversions involving CpG dinucleotides, whereas the TF model does.

    Blog text (25)
  • The codon 249 mutation we detected in HCCs is also a G to T transversion.

    Academic text (1991)
  • We set the transition/transversion ratios (ti/tv) to match the ones empirically calculated with jModeltest for each species.

    Academic text (2018)
  • Of particular note is the observation that MLEs for CpG transversions were strongly discordant between the NF and TF forms.

    Blog text (25)
  • In DNA analysis, a transversion occurs when a purine base is switched to a pyrimidine base.

  • The geneticist explained that a transversion can cause significant changes in protein synthesis.

  • Researchers observed a higher frequency of transversions compared to transitions in certain mutations.

Synonyms

gene mutation
vstransversion
  • Specialized
2 4.2

A permanent change in a gene that parents can pass to children

is a specific change swapping one base type for the other in DNA

Surface Forms

transversion singular
transversions plural

Morphology

transversion = version (opaque) = trans + version

Although morphologically formed from 'trans-' + 'version', the genetic sense (a specific nucleotide substitution type) is a technical meaning not derivable by an average learner from the components.

Etymology

Transversion comes from trans- 'across' and version 'turning'. In genetics, think of it as a 'turn across': one DNA 'letter' is changed to a letter from the other group, so the word fits this swap across types.