transversion
- noun
- /trænzˈvɜrʒən/
- Specialized
- Although neighboring effects in general are still important, prominent influences such as the elevated CpG transversion rate previously identified using the TF form are an artifact.
Examples
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Specifically, the NF model does not recognize a significant context-dependent influence on transversions involving CpG dinucleotides, whereas the TF model does.
Blog text (25) -
The codon 249 mutation we detected in HCCs is also a G to T transversion.
Academic text (1991) -
We set the transition/transversion ratios (ti/tv) to match the ones empirically calculated with jModeltest for each species.
Academic text (2018) -
Of particular note is the observation that MLEs for CpG transversions were strongly discordant between the NF and TF forms.
Blog text (25) -
In DNA analysis, a transversion occurs when a purine base is switched to a pyrimidine base.
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The geneticist explained that a transversion can cause significant changes in protein synthesis.
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Researchers observed a higher frequency of transversions compared to transitions in certain mutations.
Synonyms
A permanent change in a gene that parents can pass to children
Surface Forms
Morphology
Etymology
Transversion comes from trans- 'across' and version 'turning'. In genetics, think of it as a 'turn across': one DNA 'letter' is changed to a letter from the other group, so the word fits this swap across types.