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Glite Dictionary
transmural

transmural

8.6
Affecting the full thickness of the wall of an organ or structure
  • adjective
  • /trænzˈmjʊrəl/
  • Specialized
translation icon : transmural
  • The surgeon noted a transmural defect in the heart wall, which required immediate attention to prevent further complications.

Examples

  • In cases of Crohn's disease, the intestine may show transmural inflammation, affecting all layers of the intestinal wall.

  • In this sequel to Rabbit at Rest, which ended with the hero on his deathbed, beset with transmural infarctions and the consequences of his own appetites, Rabbit Angstrom, ambivalent hero of four,

    Fiction book (1992)

  • This would produce a substantial acute increase in left-ventricular transmural pressure and afterload by increasing the difference between intracardiac and intrathoracic pressure.

    Academic text (1991)

  • This transmural current density gradient mediates the appearance of the action potential notch, which underlies the normal J wave in the electrocardiogram (ECG) 76,77.

    Academic text (2016)

  • The possibility that sulphonylureas, which are known to block the ATP-sensitive potassium channel, interfere with this protective mechanism and thus convert a potentially subendocardial infarct into a transmural one, thereby increasing the size of the infarct, must be considered.

    Academic text (1995)

  • Transmural pressure must be carefully monitored during surgery to ensure proper blood flow through the organs.

Synonyms

perforant
vstransmural
  • Specialized
9.9

Passing through another tissue or structure in the body

extends through the whole thickness of an organ wall

Antonyms

superficial
20 5.3

Near the surface and not deep, like a small cut

How Deep

transmural
  • Specialized
8.6
superficial
20 5.3

Surface Forms

transmural positive

Morphology

transmural = mural (semi-transparent) = trans + mural

The combination 'trans-' (across) + 'mural' (relating to a wall) yields the literal sense 'across/through a wall', but the specific medical meaning 'through the full thickness of an organ wall' is specialized.

Etymology

Transmural comes from the parts trans- 'across' and mural 'wall', with mural like a wall painting. So a transmural injury or change goes through the whole thickness of the wall of an organ or other structure.